proto-oncogene proteins pim

Known as: pim kinases, proto-oncogene protein pim 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2013-2017
012320132017

Papers overview

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2016
2016
Tumorigenesis is a multistep process involving co-operation between several deregulated oncoproteins. In this study, we unravel… (More)
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2016
2016
Therapeutic strategies for the treatment of metastatic melanoma show encouraging results in the clinic; however, not all patients… (More)
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2015
2015
PIM kinases are a family of Ser/Thr kinases that are implicated in tumorigenesis. The discovery of a new class of PIM inhibitors… (More)
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2015
2015
The reference standard CX-6258 {(E)-5-chloro-3-((5-(3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)indolin-2… (More)
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Review
2015
Review
2015
The initiation and progression of human cancer is frequently linked to the uncontrolled activation of survival kinases. Two such… (More)
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2014
2014
RATIONALE The senescent cardiac phenotype is accompanied by changes in mitochondrial function and biogenesis causing impairment… (More)
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2014
2014
Adult T-cell leukemia-lymphoma (ATL), an aggressive neoplasm etiologically associated with HTLV-1, is a chemoresistant malignancy… (More)
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Review
2014
Review
2014
The PIM proteins, which were initially discovered as proviral insertion sites in Moloney-murine leukemia virus infection, are a… (More)
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Review
2014
Review
2014
The proviral insertion site in Moloney murine leukemia virus, or PIM proteins, are a family of serine/threonine kinases composed… (More)
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2013
2013
A novel series of PIM inhibitors was derived from a combined effort in natural product-inspired library generation and screening… (More)
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