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proteoglycan metabolic process

Known as: proteoglycan metabolism 
The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. [GOC:mah, ISBN… 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis
Osteoarthritis (OA), the commonest form of arthritis and a major cause of morbidity, is characterized by progressive degeneration… 
Highly Cited
2003
Highly Cited
2003
Hydrostatic pressure modulates proteoglycan metabolism in chondrocytes seeded in agarose.
OBJECTIVE To investigate the effect of isolated hydrostatic pressure on proteoglycan metabolism in chondrocytes. METHODS Bovine… 
Review
1999
Review
1999
Profile and mechanisms of gastrointestinal and other side effects of nonsteroidal anti-inflammatory drugs (NSAIDs).
Highly Cited
1997
Highly Cited
1997
Effects of Meloxicam, Compared with other NSAIDs, on Cartilage Proteoglycan Metabolism, Synovial Prostaglandin E2, and Production of Interleukins 1, 6 and 8, in Human and Porcine Explants in Organ…
Some non‐steroidal anti‐inflammatory drugs (NSAIDs) can accelerate joint damage in osteoarthritis by enhancing the production of… 
Highly Cited
1994
Highly Cited
1994
The effects of matrix compression on proteoglycan metabolism in articular cartilage explants.
Highly Cited
1990
Highly Cited
1990
Scorbutic and fasted guinea pig sera contain an insulin-like growth factor I-reversible inhibitor of proteoglycan and collagen synthesis in chick embryo chondrocytes and adult human skin fibroblasts.
Review
1989
Review
1989
Factors involved in the regulation of proteoglycan metabolism in articular cartilage.
Discussion sur l'homeostasie des proteoglycanes articulaires. Role des facteurs du serum de veau fœtal, des facteurs de… 
Highly Cited
1989
Highly Cited
1989
Independent effects of interleukin-1 on proteoglycan breakdown, proteoglycan synthesis, and prostaglandin E2 release from cartilage in organ culture.
Exposure of bovine nasal cartilage in culture to interleukin-1 (IL-1) leads to a time- and concentration-dependent stimulation of… 
Highly Cited
1988
Highly Cited
1988
The role of interleukin-1 on proteoglycan metabolism of rabbit annulus fibrosus cells cultured in vitro.
The effects of human recombinant interleukin-1 alpha (IL-1 alpha) on proteoglycan (PG) metabolism of rabbit intervertebral disc… 
Highly Cited
1985
Highly Cited
1985
Neoplastic modulation of extracellular matrix. Colon carcinoma cells release polypeptides that alter proteoglycan metabolism in colon fibroblasts.
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