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proteoglycan metabolic process
Known as:
proteoglycan metabolism
The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. [GOC:mah, ISBN…
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National Institutes of Health
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Highly Cited
2005
Highly Cited
2005
Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis
A. Young
,
Margaret M. Smith
,
+7 authors
C. Little
Arthritis Research & Therapy
2005
Corpus ID: 16233416
Osteoarthritis (OA), the commonest form of arthritis and a major cause of morbidity, is characterized by progressive degeneration…
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Highly Cited
1998
Highly Cited
1998
EFFECTS OF INTERLEUKIN‐6 ON PROLIFERATION AND PROTEOGLYCAN METABOLISM IN ARTICULAR CHONDROCYTE CULTURES
A. Jikko
,
Takashi Wakisaka
,
+5 authors
H. Fuchihata
Cell Biology International
1998
Corpus ID: 37098215
Interleukin‐6 (IL‐6) levels are markedly increased in the synovial fluid of patients with rheumatoid arthritis or osteoarthritis…
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1994
1994
An investigation of the proteoglycan metabolism of mature equine articular cartilage and its regulation by interleukin-1.
D. Platt
,
M. Bayliss
Equine Veterinary Journal
1994
Corpus ID: 39837751
The effect of human recombinant interleukin-1 beta (rhIL-1 beta) on proteoglycan metabolism was investigated in cultures of full…
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1994
1994
Site-specific cartilage changes in murine degenerative knee joint disease induced by iodoacetate and collagenase.
G. V. Osch
,
P. M. Kraan
,
W. B. Berg
1994
Corpus ID: 72382799
Degenerative joint disease was induced in the knee joints of mice by intraarticular injection of two different stimuli…
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1993
1993
In vivo effects of naproxen on composition, proteoglycan metabolism, and matrix metalloproteinase activities in canine articular cartilage
Anthony Ratcliffee
,
W. Azzo
,
F. Saed‐Nejad
,
N. Lane
,
M. Rosenwasser
,
V. Mow
Journal of Orthopaedic Research
1993
Corpus ID: 20720876
Naproxen is a nonsteroidal anti‐inflammatory drug commonly used in the clinical treatment of joint disease. In this study, its…
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1991
1991
Modulation of interleukin-1-induced alterations in cartilage proteoglycan metabolism by activation of protein kinase C.
E. Arner
,
M. Pratta
Arthritis & Rheumatism
1991
Corpus ID: 25905572
Interleukin-1 (IL-1) stimulates proteoglycan degradation and prostaglandin E2 (PGE2) release and inhibits proteoglycan synthesis…
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1990
1990
The synthesis and immobilisation of cartilage-specific proteoglycan by human chondrocytes in different concentrations of agarose.
G. Verbruggen
,
E. Veys
,
+5 authors
C. Broddelez
Clinical and Experimental Rheumatology
1990
Corpus ID: 27495006
Chondrocytes were cultured in agarose gels of different concentrations. In this in vitro model these cells synthesize tissue…
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Highly Cited
1987
Highly Cited
1987
Proteoglycan metabolism associated with mouse metanephric development: morphologic and biochemical effects of beta-D-xyloside.
J. Platt
,
D. Brown
,
K. Granlund
,
T. Oegema
,
D. Klein
Developmental Biology
1987
Corpus ID: 29106160
1984
1984
Alterations in proteoglycan metabolism in the nephrotic syndrome induced by the aminonucleoside of puromycin.
D. Klein
,
P. Dehnel
,
T. Oegema
,
D. Brown
Laboratory investigation; a journal of technical…
1984
Corpus ID: 13539233
The synthesis of intact proteoglycans and their glycosaminoglycan (GAG) side chains by isolated rat glomeruli in vitro were…
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1977
1977
Influence of sulphated glycosaminoglycans upon proteoglycan metabolism of the synovial lining cells.
G. Verbruggen
,
E. Veys
Acta rhumatologica Belgica
1977
Corpus ID: 46425888
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