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proteoglycan metabolic process

Known as: proteoglycan metabolism 
The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. [GOC:mah, ISBN… 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis
Osteoarthritis (OA), the commonest form of arthritis and a major cause of morbidity, is characterized by progressive degeneration… 
Highly Cited
1998
Highly Cited
1998
EFFECTS OF INTERLEUKIN‐6 ON PROLIFERATION AND PROTEOGLYCAN METABOLISM IN ARTICULAR CHONDROCYTE CULTURES
Interleukin‐6 (IL‐6) levels are markedly increased in the synovial fluid of patients with rheumatoid arthritis or osteoarthritis… 
1994
1994
An investigation of the proteoglycan metabolism of mature equine articular cartilage and its regulation by interleukin-1.
The effect of human recombinant interleukin-1 beta (rhIL-1 beta) on proteoglycan metabolism was investigated in cultures of full… 
1994
1994
Site-specific cartilage changes in murine degenerative knee joint disease induced by iodoacetate and collagenase.
Degenerative joint disease was induced in the knee joints of mice by intraarticular injection of two different stimuli… 
1993
1993
In vivo effects of naproxen on composition, proteoglycan metabolism, and matrix metalloproteinase activities in canine articular cartilage
Naproxen is a nonsteroidal anti‐inflammatory drug commonly used in the clinical treatment of joint disease. In this study, its… 
1991
1991
Modulation of interleukin-1-induced alterations in cartilage proteoglycan metabolism by activation of protein kinase C.
Interleukin-1 (IL-1) stimulates proteoglycan degradation and prostaglandin E2 (PGE2) release and inhibits proteoglycan synthesis… 
1990
1990
The synthesis and immobilisation of cartilage-specific proteoglycan by human chondrocytes in different concentrations of agarose.
Chondrocytes were cultured in agarose gels of different concentrations. In this in vitro model these cells synthesize tissue… 
Highly Cited
1987
Highly Cited
1987
Proteoglycan metabolism associated with mouse metanephric development: morphologic and biochemical effects of beta-D-xyloside.
1984
1984
Alterations in proteoglycan metabolism in the nephrotic syndrome induced by the aminonucleoside of puromycin.
The synthesis of intact proteoglycans and their glycosaminoglycan (GAG) side chains by isolated rat glomeruli in vitro were… 
1977
1977
Influence of sulphated glycosaminoglycans upon proteoglycan metabolism of the synovial lining cells.
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