protein deacetylase activity

Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate. [GOC:mah]
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2017
012320002017

Papers overview

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2017
2017
Obesity and diabetes are known risk factors for dementia, and it is speculated that chronic neuroinflammation contributes to this… (More)
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2015
2015
Decline in mitochondrial DNA (mtDNA) copy number, function, and accumulation of mutations and deletions have been proposed to… (More)
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2012
2012
In nonhuman primates, we previously demonstrated that a maternal high-fat diet (MHFD) induces fetal nonalcoholic fatty liver… (More)
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2012
2012
SIRT1, a NAD(+)-dependent protein deacetylase, is an important regulator in cellular stress response and energy metabolism. While… (More)
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2010
2010
SIRT3 is one of the seven mammalian sirtuin homologs of the yeast SIR2 gene. SIRT3 possesses NAD(+)-dependent protein deacetylase… (More)
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2006
2006
Sirtuin 6 (SIRT6) is a member of the sirtuin deacetylases (sirtuins), which are derivatives of the yeast Silent information… (More)
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2006
2006
Sirtuin 6 (SIRT6) is a member of the sirtuin deacetylases (sirtuins), which are derivatives of the yeast Silent information… (More)
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Highly Cited
2005
Highly Cited
2005
Conversion of vascular smooth muscle cells (SMCs) from a proliferative state to a nonproliferative, contractile state confers… (More)
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Highly Cited
2004
Highly Cited
2004
Histone deacetylase (HDAC) activity, commonly correlated with transcriptional repression, was essential for transcriptional… (More)
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Highly Cited
2000
Highly Cited
2000
The yeast Sir2 protein, required for transcriptional silencing, has an NAD(+)-dependent histone deacetylase (HDA) activity. Yeast… (More)
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