FAQ

protein adenylyltransferase activity

Known as: AMPylator, adenosine monophosphate-protein transferase activity 
Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP… (More)
National Institutes of Health

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Topic mentions per year

2014-2017
01220142017

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protein adenylylation

Related mentions per year

Related mentions per year

2014-2017
201020122014201620182020
protein adenylyltransferase activity
protein adenylylation

Papers overview

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2017
2017
Catch and arrest: exploiting the retromer by a Chlamydial effector
Three recent papers, including one by Sun et al. in this issue of Signal Transduction and Targeted Therapy, analyze the… (More)
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2015
2015
Synthesis and evaluation of 2-ethynyl-adenosine-5'-triphosphate as a chemical reporter for protein AMPylation.
Protein AMPylation is a posttranslational modification (PTM) defined as the transfer of an adenosine monophosphate (AMP) from… (More)
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2014
2014
Unfolded protein response-regulated Drosophila Fic (dFic) protein reversibly AMPylates BiP chaperone during endoplasmic reticulum homeostasis.
Drosophila Fic (dFic) mediates AMPylation, a covalent attachment of adenosine monophosphate (AMP) from ATP to hydroxyl side… (More)
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2014
2014
Inhibiting AMPylation: a novel screen to identify the first small molecule inhibitors of protein AMPylation.
Enzymatic transfer of the AMP portion of ATP to substrate proteins has recently been described as an essential mechanism of… (More)
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