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protein O-GlcNAc transferase activity

Known as: O-GlcNAc transferase, OGTase, UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase 
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Molecular Interrogation to Crack the Case of O-GlcNAc.
The O-linked β-N-acetylglucosamine (O-GlcNAc) modification, termed O-GlcNAcylation, is an essential and dynamic post… Expand
2016
2016
Identification and biological consequences of the O-GlcNAc modification of the human innate immune receptor, Nod2.
Nucleotide-binding oligomerization domain 2 (Nod2) is an intracellular receptor that can sense the bacterial peptidoglycan… Expand
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2015
2015
Interplay between troponin T phosphorylation and O-N-acetylglucosaminylation in ischaemic heart failure.
AIMS Previous studies have reported that decreased serine 208 phosphorylation of troponin T (TnTpSer208) is associated with… Expand
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2014
2014
Inhibition of O-GlcNAcase (OGA): A Potential Therapeutic Target to Treat Alzheimer's Disease.
Patent Application Title: Glycosidase Inhibitors Patent Application Number: WO 2014/159234 A1 Publication date: 2 October 2014… Expand
Highly Cited
2003
Highly Cited
2003
Localization of the O-GlcNAc transferase and O-GlcNAc-modified proteins in rat cerebellar cortex
O-linked N-acetylglucosamine (O-GlcNAc) is a ubiquitous nucleocytoplasmic protein modification that has a complex interplay with… Expand
Highly Cited
2001
Highly Cited
2001
Hyperglycemia and the O-GlcNAc transferase in rat aortic smooth muscle cells: elevated expression and altered patterns of O-GlcNAcylation.
Hyperglycemia leads to vascular disease specific to diabetes mellitus. This pathology, which results from abnormal proliferation… Expand
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