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protegrin-1

Known as: PG-1 protegrin, protegrin PG-1 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Anti-Infective AgentsAntifungal AgentsAntimicrobial Cationic Peptides

Papers overview

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Highly Cited
2014
Highly Cited
2014
Antimicrobial potency and selectivity of simplified symmetric-end peptides.
Highly Cited
2008
Highly Cited
2008
Models of toxic beta-sheet channels of protegrin-1 suggest a common subunit organization motif shared with toxic alzheimer beta-amyloid ion channels.
Antimicrobial peptides (AMPs) induce cytotoxicity by altering membrane permeability. The electrical properties of membrane… 
Highly Cited
2008
Highly Cited
2008
On the nature of antimicrobial activity: a model for protegrin-1 pores.
We conducted over 150 ns of simulation of a protegrin-1 octamer pore in a lipid bilayer composed of palmitoyloleoyl… 
Highly Cited
2006
Highly Cited
2006
Interaction of protegrin-1 with lipid bilayers: membrane thinning effect.
Protegrins (PG) are important in defending host tissues, preventing infection via an attack on the membrane surface of invading… 
Highly Cited
2005
Highly Cited
2005
Membrane-disruptive abilities of beta-hairpin antimicrobial peptides correlate with conformation and activity: a 31P and 1H NMR study.
Highly Cited
2004
Highly Cited
2004
Solid-state NMR investigation of the selective disruption of lipid membranes by protegrin-1.
The interaction of a beta-hairpin antimicrobial peptide, protegrin-1 (PG-1), with various lipid membranes is investigated by (31… 
Highly Cited
2002
Highly Cited
2002
Solid-state NMR investigations of peptide-lipid interaction and orientation of a beta-sheet antimicrobial peptide, protegrin.
Protegrin-1 (PG-1) is a broad-spectrum beta-sheet antimicrobial peptide found in porcine leukocytes. The mechanism of action and… 
Highly Cited
2000
Highly Cited
2000
Membrane thinning effect of the beta-sheet antimicrobial protegrin.
Lipid bilayers containing the antimicrobial peptide protegrin-1 (PG-1) were studied by lamellar X-ray diffraction. Previously, we… 
Highly Cited
1998
Highly Cited
1998
Multiple states of beta-sheet peptide protegrin in lipid bilayers.
Protegrin-1 (PG-1), a beta-sheet antimicrobial peptide, was studied in aligned lipid bilayers by oriented circular dichroism (OCD… 
Highly Cited
1996
Highly Cited
1996
Synthesis and solution structure of the antimicrobial peptide protegrin-1.
Protegrins are members of a family of five Cys-rich, cationic antimicrobial peptides recently isolated from porcine cells. We… 
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