proteasome assembly

Known as: proteasome complex assembly, proteasome maturation 
The aggregation, arrangement and bonding together of a mature, active proteasome complex. [GOC:go_curators, PMID:10872471]
National Institutes of Health

Papers overview

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2015
2015
Proteasome inhibition represents a promising strategy of cancer pharmacotherapy, but resistant tumor cells often emerge. Here we… (More)
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2013
2013
The 26S proteasome has an elaborate structure, consisting of 33 different subunits that form the 20S core particle capped by the… (More)
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2011
2011
In this study we determine that the Not4 E3 ligase is important for proteasome integrity. Consequently, deletion of Not4 leads to… (More)
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2009
2009
Proteasome regulates diverse cellular functions by eliminating ubiquitinated proteins. Protein kinase A (PKA) is a key regulator… (More)
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Highly Cited
2007
Highly Cited
2007
The 20S proteasome is the catalytic core of the 26S proteasome, a central enzyme in the ubiquitin-proteasome system. Its assembly… (More)
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Highly Cited
2005
Highly Cited
2005
Peptide generation by the proteasome is rate-limiting in MHC class I-restricted antigen presentation in response to IFN-gamma… (More)
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Highly Cited
2005
Highly Cited
2005
The proteasome is the major cellular proteolytic machinery responsible for the degradation of both normal and damaged proteins… (More)
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Highly Cited
2003
Highly Cited
2003
The 26 S proteasome is a high molecular mass proteinase complex that is built by at least 32 different protein subunits. Such… (More)
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2000
2000
Biogenesis of mammalian 20 S proteasomes occurs via precursor complexes containing alpha and unprocessed beta subunits. A human… (More)
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Highly Cited
1998
Highly Cited
1998
We report the discovery of a short-lived chaperone that is required for the correct maturation of the eukaryotic 20S proteasome… (More)
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