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proteasome activator complex location

Known as: PA28, proteasome activator complex 
A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex. [GOC:rb]
National Institutes of Health

Papers overview

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Review
2005
Review
2005
Summary:  The proteasome system is a central component of a cascade of proteolytic processing steps required to generate… Expand
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Review
2004
Review
2004
MHC-class-I-presented peptides are predominantly generated by the proteasome system. IFN-gamma strongly influences the processing… Expand
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Highly Cited
2003
Highly Cited
2003
Parkinson's disease (PD) is characterized pathologically by preferential degeneration of the dopaminergic neurons in the… Expand
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Review
2002
Review
2002
Three different proteolytic processes have been shown to be important in the generation of antigenic peptides displayed on MHC… Expand
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Review
2001
Review
2001
Interferons (IFNs) are a family of secreted proteins with antiviral, antiproliferative and immunomodulatory activities. The… Expand
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Highly Cited
2000
Highly Cited
2000
Most of the non-lysosomal proteolysis that occurs in eukaryotic cells is performed by a nonspecific and abundant barrel-shaped… Expand
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Highly Cited
1999
Highly Cited
1999
Although the number of pathologies known to arise from the inappropriate folding of proteins continues to grow, mechanisms… Expand
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Review
1998
Review
1998
Classical class I molecules assemble in the endoplasmic reticulum (ER) with peptides mostly generated from cytosolic proteins by… Expand
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Highly Cited
1996
Highly Cited
1996
CYTOTOXIC T cells recognize viral proteins as peptide fragments which are produced in the cytosol and transported on major… Expand
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Highly Cited
1992
Highly Cited
1992
A protein that greatly stimulates the multiple peptidase activities of the 20 S proteasome (also known as macropain, the… Expand
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