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proteasome activator complex location
Known as:
PA28
, proteasome activator complex
A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex. [GOC:rb]
National Institutes of Health
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2012
2012
Dopaminergic therapies modulate the T‐CELL proteome of patients with Parkinson's disease
T. Alberio
,
A. C. Pippione
,
+5 authors
M. Fasano
IUBMB Life - A Journal of the International Union…
2012
Corpus ID: 10754218
Dopamine receptor agonists and L‐dihydroxyphenylalanine (L‐DOPA) counteract dopamine loss in the striatum and are therefore used…
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Review
2003
Review
2003
The components of the proteasome system and their role in MHC class I antigen processing.
Elke Krüger
,
Ulrike Kuckelkorn
,
A. Sijts
,
P. Kloetzel
Reviews of Physiology, Biochemistry and…
2003
Corpus ID: 44633538
By generating peptides from intracellular antigens which are then presented to T cells, the ubiquitin/26S proteasome system plays…
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Highly Cited
2002
Highly Cited
2002
The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing.
Xiaohua Huang
,
U. Seifert
,
+6 authors
W. Dubiel
Journal of Molecular Biology
2002
Corpus ID: 30729642
Highly Cited
2001
Highly Cited
2001
gamma-Interferon decreases the level of 26 S proteasomes and changes the pattern of phosphorylation.
S. Bose
,
P. Brooks
,
G. Mason
,
A. Rivett
Biochemical Journal
2001
Corpus ID: 25494276
In mammalian cells proteasomes can be activated by two different types of regulatory complexes which bind to the ends of the…
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2000
2000
Properties of the nuclear proteasome activator PA28gamma (REGgamma).
S. Wilk
,
W. Chen
,
R. Magnusson
Archives of Biochemistry and Biophysics
2000
Corpus ID: 25077523
PA28 or 11S REG is a proteasome activator composed of homologous alpha- and beta-subunits and predominantly found in the cytosol…
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Review
1999
Review
1999
Phosphorylation of proteasomes in mammalian cells
S. Bose
,
G. Mason
,
A. Rivett
Molecular Biology Reports
1999
Corpus ID: 19288514
Abstract20S proteasomes are large (700 kDa) proteinase complexes which form the central catalytic core of larger complexes (26S…
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Highly Cited
1998
Highly Cited
1998
Contribution of Proline Residue for Efficient Production of MHC Class I Ligands by Proteasomes*
N. Shimbara
,
K. Ogawa
,
+5 authors
Keiji Tanaka
Journal of Biological Chemistry
1998
Corpus ID: 757747
Proteasomes are processing enzymes capable of generating major histocompatibility complex (MHC) class I ligands, but the…
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Highly Cited
1997
Highly Cited
1997
Structure of the proteasome activator REGalpha (PA28alpha).
J. Knowlton
,
S. Johnston
,
+4 authors
C. Hill
Nature
1997
Corpus ID: 20983728
The specificity of the 20S proteasome, which degrades many intracellular proteins, is regulated by protein complexes that bind to…
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Highly Cited
1996
Highly Cited
1996
Activation of the multicatalytic endopeptidase by oxidants. Effects on enzyme structure.
Peter R. Strack
,
L. Waxman
,
Julie M. Fagan
Biochemistry
1996
Corpus ID: 43346103
It is well established that the functional properties of proteins can be compromised by oxidative damage and, in vivo, proteins…
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Highly Cited
1994
Highly Cited
1994
PA28, an activator of the 20 S proteasome, is composed of two nonidentical but homologous subunits.
J. Mott
,
B. Pramanik
,
C. Moomaw
,
S. Afendis
,
G. Demartino
,
C. Slaughter
Journal of Biological Chemistry
1994
Corpus ID: 28122687
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