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proteasome activator complex location

Known as: PA28, proteasome activator complex 
A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex. [GOC:rb]
National Institutes of Health

Papers overview

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2012
2012
Dopaminergic therapies modulate the T‐CELL proteome of patients with Parkinson's disease
Dopamine receptor agonists and L‐dihydroxyphenylalanine (L‐DOPA) counteract dopamine loss in the striatum and are therefore used… 
Review
2003
Review
2003
The components of the proteasome system and their role in MHC class I antigen processing.
By generating peptides from intracellular antigens which are then presented to T cells, the ubiquitin/26S proteasome system plays… 
Highly Cited
2002
Highly Cited
2002
The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing.
Highly Cited
2001
Highly Cited
2001
gamma-Interferon decreases the level of 26 S proteasomes and changes the pattern of phosphorylation.
In mammalian cells proteasomes can be activated by two different types of regulatory complexes which bind to the ends of the… 
2000
2000
Properties of the nuclear proteasome activator PA28gamma (REGgamma).
PA28 or 11S REG is a proteasome activator composed of homologous alpha- and beta-subunits and predominantly found in the cytosol… 
Review
1999
Review
1999
Phosphorylation of proteasomes in mammalian cells
Abstract20S proteasomes are large (700 kDa) proteinase complexes which form the central catalytic core of larger complexes (26S… 
Highly Cited
1998
Highly Cited
1998
Contribution of Proline Residue for Efficient Production of MHC Class I Ligands by Proteasomes*
Proteasomes are processing enzymes capable of generating major histocompatibility complex (MHC) class I ligands, but the… 
Highly Cited
1997
Highly Cited
1997
Structure of the proteasome activator REGalpha (PA28alpha).
The specificity of the 20S proteasome, which degrades many intracellular proteins, is regulated by protein complexes that bind to… 
Highly Cited
1996
Highly Cited
1996
Activation of the multicatalytic endopeptidase by oxidants. Effects on enzyme structure.
It is well established that the functional properties of proteins can be compromised by oxidative damage and, in vivo, proteins… 
Highly Cited
1994
Highly Cited
1994
PA28, an activator of the 20 S proteasome, is composed of two nonidentical but homologous subunits.
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