FAQ

prostate cancer antigen 3, human

Known as: Non-Protein Coding RNA 19, PCA3, human, DD3 antigen, human 
Prostate cancer antigen 3 (~4 kb) is encoded by the human PCA3 gene. This non-coding RNA may be involved in prostate carcinoma.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2018
010203019852018

Related topics

Related topics

5 relations

Broader (1)

Antigens, Neoplasm
Homo sapiensPCA3 geneProstate carcinomaTumor Markers

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
prostate cancer antigen 3, human
Prostate carcinoma
Tumor Markers
Homo sapiens
PCA3 gene
Antigens, Neoplasm

Papers overview

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Highly Cited
2016
Highly Cited
2016
Urine TMPRSS2:ERG Plus PCA3 for Individualized Prostate Cancer Risk Assessment.
BACKGROUND TMPRSS2:ERG (T2:ERG) and prostate cancer antigen 3 (PCA3) are the most advanced urine-based prostate cancer (PCa… (More)
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Highly Cited
2014
Highly Cited
2014
Prospective multicentre evaluation of PCA3 and TMPRSS2-ERG gene fusions as diagnostic and prognostic urinary biomarkers for prostate cancer.
BACKGROUND Prostate cancer antigen 3 (PCA3) and v-ets erythroblastosis virus E26 oncogene homolog (TMPRSS2-ERG) gene fusions are… (More)
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Highly Cited
2013
Highly Cited
2013
Combining urinary detection of TMPRSS2:ERG and PCA3 with serum PSA to predict diagnosis of prostate cancer.
OBJECTIVES We sought to develop a clinical algorithm combining serum PSA with detection of TMPRSS2:ERG fusion and PCA3 in urine… (More)
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Highly Cited
2011
Highly Cited
2011
Critical assessment of preoperative urinary prostate cancer antigen 3 on the accuracy of prostate cancer staging.
BACKGROUND Knowledge about the staging significance of the prostate cancer antigen 3 (PCA3) score to better identify pathologic… (More)
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Highly Cited
2009
Highly Cited
2009
Prostate cancer gene 3 (PCA3): development and internal validation of a novel biopsy nomogram.
BACKGROUND Urinary prostate cancer gene 3 (PCA3) represents a promising novel marker of prostate cancer detection. OBJECTIVE To… (More)
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Highly Cited
2008
Highly Cited
2008
A first-generation multiplex biomarker analysis of urine for the early detection of prostate cancer.
Although prostate-specific antigen (PSA) serum level is currently the standard of care for prostate cancer screening in the… (More)
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Highly Cited
2008
Highly Cited
2008
PCA3: a molecular urine assay for predicting prostate biopsy outcome.
PURPOSE A urinary assay for PCA3, an mRNA that is highly over expressed in prostate cancer cells, has shown usefulness as a… (More)
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Highly Cited
2008
Highly Cited
2008
PCA3 molecular urine assay correlates with prostate cancer tumor volume: implication in selecting candidates for active surveillance.
PURPOSE Prostate cancer gene 3 (PCA3) has shown promise as a molecular marker in prostate cancer detection. We assessed the… (More)
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Highly Cited
2007
Highly Cited
2007
PCA3 molecular urine assay for prostate cancer in men undergoing repeat biopsy.
OBJECTIVES Men with elevated serum prostate-specific antigen (PSA) levels and negative prostate biopsy findings present a dilemma… (More)
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Highly Cited
2006
Highly Cited
2006
APTIMA PCA3 molecular urine test: development of a method to aid in the diagnosis of prostate cancer.
BACKGROUND Prostate cancer gene 3 (PCA3) encodes a prostate-specific mRNA that has shown promise as a prostate cancer diagnostic… (More)
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