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prostate cancer antigen 3, human

Known as: Non-Protein Coding RNA 19, PCA3, human, DD3 antigen, human 
Prostate cancer antigen 3 (~4 kb) is encoded by the human PCA3 gene. This non-coding RNA may be involved in prostate carcinoma.
National Institutes of Health

Related topics

Related topics

5 relations

Broader (1)

Antigens, Neoplasm
Homo sapiensPCA3 geneProstate carcinomaTumor Markers

Papers overview

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Highly Cited
2014
Highly Cited
2014
Prospective multicentre evaluation of PCA3 and TMPRSS2-ERG gene fusions as diagnostic and prognostic urinary biomarkers for prostate cancer.
BACKGROUND Prostate cancer antigen 3 (PCA3) and v-ets erythroblastosis virus E26 oncogene homolog (TMPRSS2-ERG) gene fusions are… Expand
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Highly Cited
2011
Highly Cited
2011
Prostate cancer antigen 3 score accurately predicts tumour volume and might help in selecting prostate cancer patients for active surveillance.
BACKGROUND The optimal selection of prostate cancer (PCa) patients for active surveillance (AS) is currently being debated… Expand
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Highly Cited
2011
Highly Cited
2011
Critical assessment of preoperative urinary prostate cancer antigen 3 on the accuracy of prostate cancer staging.
BACKGROUND Knowledge about the staging significance of the prostate cancer antigen 3 (PCA3) score to better identify pathologic… Expand
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Highly Cited
2008
Highly Cited
2008
PCA3: a molecular urine assay for predicting prostate biopsy outcome.
PURPOSE A urinary assay for PCA3, an mRNA that is highly over expressed in prostate cancer cells, has shown usefulness as a… Expand
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Highly Cited
2008
Highly Cited
2008
A first-generation multiplex biomarker analysis of urine for the early detection of prostate cancer.
Although prostate-specific antigen (PSA) serum level is currently the standard of care for prostate cancer screening in the… Expand
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Highly Cited
2008
Highly Cited
2008
Clinical utility of the PCA3 urine assay in European men scheduled for repeat biopsy.
BACKGROUND The Prostate CAncer gene 3 (PCA3) assay has shown promise as an aid in prostate cancer (pCA) diagnosis in identifying… Expand
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Highly Cited
2007
Highly Cited
2007
PCA3 molecular urine assay for prostate cancer in men undergoing repeat biopsy.
OBJECTIVES Men with elevated serum prostate-specific antigen (PSA) levels and negative prostate biopsy findings present a dilemma… Expand
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Highly Cited
2007
Highly Cited
2007
Detection of TMPRSS2-ERG Fusion Transcripts and Prostate Cancer Antigen 3 in Urinary Sediments May Improve Diagnosis of Prostate Cancer
Purpose: Early detection of prostate cancer can increase the curative success rate for prostate cancer. We studied the diagnostic… Expand
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Highly Cited
2006
Highly Cited
2006
APTIMA PCA3 molecular urine test: development of a method to aid in the diagnosis of prostate cancer.
BACKGROUND Prostate cancer gene 3 (PCA3) encodes a prostate-specific mRNA that has shown promise as a prostate cancer diagnostic… Expand
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Highly Cited
2003
Highly Cited
2003
DD3PCA3-based molecular urine analysis for the diagnosis of prostate cancer
Abstract Background: DD3 PCA3 is the most prostate cancer-specific gene described to date. To assess the clinical utility of DD3… Expand
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