proguanylin
National Institutes of Health
Papers overview
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This study investigated the role of prouroguanylin (ProUGN) and proguanylin (ProGN), members of a novel class of peptides with…
The aim of our work was to develop an assay for the determination of proguanylin in human blood, and investigate its levels in…
In contrast to their prohormones the mature peptide hormones guanylin and uroguanylin are not able to fold to their native…
The intestinal peptide hormone guanylin circulates mainly as its corresponding prohormone of 94 amino acids and is the first…
Guanylin, an intestinal peptide hormone and endogenous ligand of guanylyl cyclase C, is produced as the corresponding prohormone…
The mechanisms of proguanylin synthesis and secretion in the intestine are incompletely understood. We designed an in vitro model…
Kita, Toshihiro, Kazuo Kitamura, Junichiro Sakata, and Tanenao Eto. Marked increase of guanylin secretion in response to salt…