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precorrin-6A synthase (deacetylating) activity

Known as: CobF, S-adenosyl-L-methionine:precorrin-5 C1-methyltransferase (deacetylating), precorrin-6X synthase (deacetylating) activity 
Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O + precorrin-5 = S-adenosyl-L-homocysteine + acetate + 2 H(+) + precorrin-6X. [EC:2.1.1.152… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Sirtinol promotes PEPCK1 degradation and inhibits gluconeogenesis by inhibiting deacetylase SIRT2
Phosphoenolpyruvate carboxykinase 1 (PEPCK1) is the critical enzyme for gluconeogenesis and is linked with type II diabetes… Expand
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2015
2015
Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs.
Activation of Sirtuin1 (Sirt1), an nicotinamide adenine dinucleotide oxidized-dependent deacetylase, by natural or synthetic… Expand
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Highly Cited
2012
Highly Cited
2012
Coronary versus carotid blood flow and coronary perfusion pressure in a pig model of prolonged cardiac arrest treated by different modes of venoarterial ECMO and intraaortic balloon counterpulsation
IntroductionExtracorporeal membrane oxygenation (ECMO) is increasingly used in cardiac arrest (CA). Adequacy of carotid and… Expand
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Highly Cited
2011
Highly Cited
2011
Synthesis and modification of thermoresponsive poly(oligo(ethylene glycol) methacrylate) via catalytic chain transfer polymerization and thiol–ene Michael addition
Various poly(oligo(ethylene glycol) methyl ether methacrylate)s (POEGMEMAs) have been prepared by Catalytic Chain Transfer… Expand
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Highly Cited
2003
Highly Cited
2003
Comparative Genomics of the Vitamin B12 Metabolism and Regulation in Prokaryotes*
Using comparative analysis of genes, operons, and regulatory elements, we describe the cobalamin (vitamin B12) biosynthetic… Expand
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Highly Cited
1998
Highly Cited
1998
Cobalamin (vitamin B12) biosynthesis: identification and characterization of a Bacillus megaterium cobI operon.
A 16 kb DNA fragment has been isolated from a Bacillus megaterium genomic library and fully sequenced. The fragment contains 15… Expand
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Highly Cited
1994
Highly Cited
1994
Examination of the role of nitric oxide for the hypercapnic rise of cerebral blood flow in rats.
We examined the effect of nitric oxide synthase (NOS) inhibition and tetrodotoxin (TTX) on the increase of cerebral blood flow… Expand
Highly Cited
1993
Highly Cited
1993
Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans.
Studies with cell-free protein preparations from a series of recombinant strains of Pseudomonas denitrificans demonstrated that… Expand
1992
1992
Spreading depression induces prolonged reduction of cortical blood flow reactivity in the rat
The purpose of the present study was to examine the dynamic aspects of the cerebrovascular events occurring during and up to 2 h… Expand
Highly Cited
1990
Highly Cited
1990
Genetic and sequence analysis of an 8.7-kilobase Pseudomonas denitrificans fragment carrying eight genes involved in transformation of precorrin-2 to cobyrinic acid.
A 8.7-kilobase DNA fragment carrying Pseudomonas denitrificans cob genes has been sequenced. The nucleotide sequence and the… Expand
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