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precorrin-2 dehydrogenase activity

Known as: precorrin-2:NAD+ oxidoreductase activity, dihydrosirohydrochlorin dehydrogenase activity, precorrin-2 oxidase activity 
Catalysis of the reaction: NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin. [EC:1.3.1.76, RHEA:15616]
National Institutes of Health

Papers overview

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2006
2006
Requirement of Staphylococcus aureus ATP-binding cassette-ATPase FhuC for iron-restricted growth and evidence that it functions with more than one iron transporter.
In Staphylococcus aureus, fhuCBG encodes an ATP-binding cassette (ABC) transporter that is required for the transport of iron(III… Expand
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2004
2004
Structure/function studies on a S-adenosyl-L-methionine-dependent uroporphyrinogen III C methyltransferase (SUMT), a key regulatory enzyme of tetrapyrrole biosynthesis.
The crystallographic structure of the Pseudomonas denitrificans S-adenosyl-L-methionine-dependent uroporphyrinogen III… Expand
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2004
2004
Molecular cloning and functional analysis of the cysG and nirB genes of Escherichia coli K12, two closely-linked genes required for NADH-dependent nitrite reductase activity
SummaryWe have cloned two genes, nirB+and cysG+which are required for NADH-dependent nitrite reductase to be active, from the 74… Expand
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2003
2003
Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium.
In Bacillus megaterium, the hemAXBCDL genes were isolated and were found to be highly similar to the genes from Bacillus subtilis… Expand
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1997
1997
A role for Salmonella typhimurium cbiK in cobalamin (vitamin B12) and siroheme biosynthesis.
The role of cbiK, a gene found encoded within the Salmonella typhimurium cob operon, has been investigated by studying its in… Expand
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1997
1997
Siroheme biosynthesis in Saccharomyces cerevisiae requires the products of both the MET1 and MET8 genes.
Siroheme is a uroporphyrinogen III-derivative used by sulfite reductase as a prosthetic group. We investigated in Saccharomyces… Expand
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1996
1996
Evidence that the CysG protein catalyzes the first reaction specific to B12 synthesis in Salmonella typhimurium, insertion of cobalt.
The cysG gene of Salmonella typhimurium is involved in synthesis of both cobalamin (B12) and siroheme (a cofactor required for… Expand
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1993
1993
Genetic structure and regulation of the cysG gene in Salmonella typhimurium.
Siroheme, a cofactor of both sulfite and nitrite reductase in Salmonella typhimurium, requires the cysG gene for its synthesis… Expand
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1992
1992
Transcriptional control, translation and function of the products of the five open reading frames of the Escherichia coli nir operon.
Five open reading frames designated nirB, nirD, nirE, nirC and cysG have been identified from the DNA sequence of the Escherichia… Expand
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1982
1982
Corneal epithelial cell--derived thymocyte-activating factor (CETAF).
Supernatants of a primary rabbit corneal epithelial cell culture and an established corneal cell line (SIRC) were assayed for… Expand
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