pre-miRNA

Known as: Pre-MicroRNA, pre miRNA 
The pre-miRNA is an oligoribonucleotide intermediate of nuclear transcription that is further processed cytosolically by the Dicer enzyme to form 20… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2018
020406020022018

Papers overview

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Highly Cited
2010
Highly Cited
2010
Dicer is a central enzyme in microRNA (miRNA) processing. We identified a Dicer-independent miRNA biogenesis pathway that uses… (More)
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Highly Cited
2010
Highly Cited
2010
The nucleolytic activity of animal Argonaute proteins is deeply conserved, despite its having no obvious role in microRNA… (More)
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Highly Cited
2009
Highly Cited
2009
As key regulators in cellular functions, microRNAs (miRNAs) themselves need to be tightly controlled. Lin28, a pluripotency… (More)
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Highly Cited
2009
Highly Cited
2009
MOTIVATION In this article, we show that the classification of human precursor microRNA (pre-miRNAs) hairpins from both genome… (More)
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Highly Cited
2005
Highly Cited
2005
RNA interference (RNAi) is mediated by RNA-induced silencing complexes (RISCs), which are guided by microRNAs (miRNAs) or short… (More)
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Highly Cited
2005
Highly Cited
2005
RNA interference is implemented through the action of the RNA-induced silencing complex (RISC). Although Argonaute2 has been… (More)
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Highly Cited
2004
Highly Cited
2004
microRNAs (miRNAs) are widespread among eukaryotes, and studies in several systems have revealed that miRNAs can regulate… (More)
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Highly Cited
2004
Highly Cited
2004
We show, with miR171, that plant miRNA genes are modular independent transcription units in which the fold-back pre-miRNA is… (More)
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Highly Cited
2003
Highly Cited
2003
MicroRNAs (miRNAs) are initially expressed as long transcripts that are processed in the nucleus to yield approximately 65… (More)
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Highly Cited
2003
Highly Cited
2003
Hundreds of small RNAs of approximately 22 nucleotides, collectively named microRNAs (miRNAs), have been discovered recently in… (More)
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