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posterior neuropore closure

The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube… Expand
National Institutes of Health

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neuropore closure

Papers overview

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2012
2012
Prenatal Ablation of Nicotinic Receptor alpha7 Cell Lineages Produces Lumbosacral Spina Bifida the Severity of Which is Modified by Choline and Nicotine Exposure
Lumbosacral spina bifida is a common debilitating birth defect whose multiple causes are poorly understood. Here, we provide the… Expand
Highly Cited
2004
Highly Cited
2004
Development of the posterior neural tube in human embryos
Development of the posterior neural tube (PNT) in human embryos is a complicated process that involves both primary and secondary… Expand
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2004
2004
Deceleration and acceleration in the rate of posterior neuropore closure during neurulation in the curly tail (ct) mouse embryo
SummaryCurly tail (ct) is a mouse mutant producing spinal neural tube defects as a result of delayed closure of the posterior… Expand
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Highly Cited
2002
Highly Cited
2002
Axial progenitors with extensive potency are localised to the mouse chordoneural hinge.
Elongation of the mouse anteroposterior axis depends on a small population of progenitors initially located in the primitive… Expand
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2002
2002
Heparan sulphate proteoglycans and spinal neurulation in the mouse embryo.
Heparan sulphate proteoglycans have been implicated in the binding and presentation of several growth factors to their receptors… Expand
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Highly Cited
1997
Highly Cited
1997
Genetic patterning of the developing mouse tail at the time of posterior neuropore closure
Posterior neuropore (PNP) closure coincides with the end of gastrulation, marking the end of primary neurulation and primary body… Expand
Highly Cited
1995
Highly Cited
1995
The T gene is necessary for normal mesodermal morphogenetic cell movements during gastrulation.
The T (Brachyury) deletion in mouse is responsible for defective primitive streak and notochord morphogenesis, leading to a… Expand
Highly Cited
1989
Highly Cited
1989
Does lumbosacral spina bifida arise by failure of neural folding or by defective canalisation?
The aim of this study was to determine whether open lumbosacral spina bifida results from an abnormality of neural folding… Expand
Highly Cited
1988
Highly Cited
1988
Prevention of spinal neural tube defects in the mouse embryo by growth retardation during neurulation.
Homozygous mutant curly tail mouse embryos developing spinal neural tube defects (NTD) exhibit a cell-type-specific abnormality… Expand
Highly Cited
1982
Highly Cited
1982
Neural tube development in mutant (curly tail) and normal mouse embryos: the timing of posterior neuropore closure in vivo and in vitro.
A dye-injection technique has been used to determine the developmental stage at which posterior neuropore (PNP) closure occurs in… Expand
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