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ponkoranol

National Institutes of Health

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Thiophenes

Papers overview

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2011
2011
Probing the intestinal α-glucosidase enzyme specificities of starch-digesting maltase-glucoamylase and sucrase-isomaltase: synthesis and inhibitory properties of 3'- and 5'-maltose-extended de-O…
The synthesis and glucosidase inhibitory activities of two C-3'- and C-5'-β-maltose-extended analogues of the naturally occurring… 
2010
2010
Potent glucosidase inhibitors: de-O-sulfonated ponkoranol and its stereoisomer.
Ponkoranol, a glucosidase inhibitor isolated from the plant Salacia reticulata, comprises a sulfonium ion with an internal… 
2010
2010
Probing the active-site requirements of human intestinal N-terminal maltase glucoamylase: the effect of replacing the sulfate moiety by a methyl ether in ponkoranol, a naturally occurring…
2010
2010
Capillary zone electrophoresis method for the separation of glucosidase inhibitors in extracts of Salacia reticulata, a plant used in ayurvedic treatments of type-2 diabetes.
A simple and reproducible capillary-zone electrophoresis (CZE) method was developed for the separation and quantitation of… 
2008
2008
Studies directed toward the stereochemical structure determination of the naturally occurring glucosidase inhibitor, kotalanol: synthesis and inhibitory activities against human maltase glucoamylase…
The synthesis of new seven-carbon, chain-extended sulfonium salts of 1,4-anhydro-4-thio- d-arabinitol, analogues of the naturally… 
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