polyglutamine

Known as: poly(glutamine), polyQ 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The causes of amyotrophic lateral sclerosis (ALS), a devastating human neurodegenerative disease, are poorly understood, although… (More)
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Highly Cited
2007
Highly Cited
2007
Expanded polyglutamine 72 repeat (polyQ72) aggregates induce endoplasmic reticulum (ER) stress-mediated cell death with caspase… (More)
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Highly Cited
2004
Highly Cited
2004
Huntington disease is one of nine inherited neurodegenerative disorders caused by a polyglutamine tract expansion. Expanded… (More)
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Highly Cited
2003
Highly Cited
2003
NEUROSCIENCE. For the article ‘‘Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded… (More)
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Highly Cited
2002
Highly Cited
2002
Protein conformational disorders (PCDs), such as Alzheimer's disease, Huntington's disease (HD), Parkinson's disease and… (More)
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Highly Cited
2002
Highly Cited
2002
Expansion of CAG trinucleotide repeats that encode polyglutamine is the underlying cause of at least nine inherited human… (More)
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Highly Cited
2001
Highly Cited
2001
Proteins with expanded polyglutamine repeats cause Huntington's disease and other neurodegenerative diseases. Transcriptional… (More)
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Highly Cited
1999
Highly Cited
1999
At least eight inherited human neurodegenerative diseases are caused by expansion of a polyglutamine domain within the respective… (More)
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Highly Cited
1998
Highly Cited
1998
Transgenic mice carrying the spinocerebellar ataxia type 1 (SCA1) gene, a polyglutamine neurodegenerative disorder, develop… (More)
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Highly Cited
1997
Highly Cited
1997
The mechanism by which an elongated polyglutamine sequence causes neurodegeneration in Huntington's disease (HD) is unknown. In… (More)
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