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poly(gamma-glutamic acid)
Known as:
gamma-PGA
, Poly-gamma Glutamic Acid
, Poly-gamma-glutamate
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A water-soluble and biodegradable polymer naturally synthesized by various strains of Bacillus and composed of D- and L-glutamic acid polymerized via…
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National Institutes of Health
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Related topics
Related topics
3 relations
NCIt Antineoplastic Agent Terminology
analogs & derivatives
Broader (1)
Polyglutamic Acid
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Enteric-coated capsules filled with freeze-dried chitosan/poly(gamma-glutamic acid) nanoparticles for oral insulin delivery.
K. Sonaje
,
Yi-Jia Chen
,
+6 authors
Hsing‐Wen Sung
Biomaterials
2010
Corpus ID: 22120482
Highly Cited
2008
Highly Cited
2008
Multi-ion-crosslinked nanoparticles with pH-responsive characteristics for oral delivery of protein drugs.
Yu-Hsin Lin
,
K. Sonaje
,
+4 authors
Hsing‐Wen Sung
Journal of Controlled Release
2008
Corpus ID: 23206639
Highly Cited
2008
Highly Cited
2008
Oral delivery of peptide drugs using nanoparticles self-assembled by poly(gamma-glutamic acid) and a chitosan derivative functionalized by trimethylation.
F. Mi
,
Yongtai Wu
,
+5 authors
Hsing‐Wen Sung
Bioconjugate chemistry
2008
Corpus ID: 821437
In the study, chitosan (CS) was conjugated with trimethyl groups for the synthesis of N-trimethyl chitosan (TMC) polymers with…
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Highly Cited
2007
Highly Cited
2007
Targeting of Antigen to Dendritic Cells with Poly(γ-Glutamic Acid) Nanoparticles Induces Antigen-Specific Humoral and Cellular Immunity1
T. Uto
,
Xin Wang
,
+4 authors
M. Baba
Journal of Immunology
2007
Corpus ID: 22402234
Nanoparticles are considered to be efficient tools for inducing potent immune responses by an Ag carrier. In this study, we…
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Highly Cited
2007
Highly Cited
2007
Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery.
Yu-Hsin Lin
,
F. Mi
,
+4 authors
Hsing‐Wen Sung
Biomacromolecules
2007
Corpus ID: 8174780
Nanoparticles (NPs) composed of chitosan (CS) and poly(gamma-glutamic acid) (gamma-PGA) were prepared by a simple ionic-gelation…
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Highly Cited
2007
Highly Cited
2007
Genome-Wide Identification of Francisella tularensis Virulence Determinants
Jingliang Su
,
Jun Yang
,
Daimin Zhao
,
T. Kawula
,
J. Banas
,
Jing-Ren Zhang
Infection and Immunity
2007
Corpus ID: 27844413
ABSTRACT Francisella tularensis is a gram-negative pathogen that causes life-threatening infections in humans and has potential…
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Highly Cited
2005
Highly Cited
2005
Defining the genetic differences between wild and domestic strains of Bacillus subtilis that affect poly‐γ‐dl‐glutamic acid production and biofilm formation
N. Stanley
,
B. Lazazzera
Molecular Microbiology
2005
Corpus ID: 24044988
Biofilms are communities of microbial cells that are encased in a self‐produced, polymeric matrix and are adherent to a…
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Review
2004
Review
2004
Biomedical applications of chemically and microbiologically synthesized poly(glutamic acid) and poly(lysine).
I. Shih
,
Y. Van
,
M. Shen
Mini-Reviews in Medical Chemistry
2004
Corpus ID: 21873585
This review article deals with the synthesis, physiochemical properties, and potential biomedical applications of two homo-poly…
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Highly Cited
1998
Highly Cited
1998
Effects of glucose and glycerol on gamma-poly(glutamic acid) formation by Bacillus licheniformis ATCC 9945a.
Young H. Ko
,
Richard A. Gross
Biotechnology and Bioengineering
1998
Corpus ID: 7306113
Bacillus licheniformis ATCC 9945a is one of the bacterial strains that produce gamma-poly(glutamic acid) (gamma-PGA). The use of…
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Highly Cited
1996
Highly Cited
1996
Effects of pH and aeration on gamma-poly(glutamic acid) formation by Bacillus licheniformis in controlled batch fermentor cultures.
A. Cromwick
,
G. A. Birrer
,
Richard A. Gross
Biotechnology and Bioengineering
1996
Corpus ID: 20688247
Bacillus licheniformis ATCC 9945A was grown on Medium E in batch fermentations in which the pH was maintained at 5.5., 6.5, 7.4…
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