FAQ

plasmacytoid dendritic cell activation

A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble… (More)

Topic mentions per year

Topic mentions per year

2005-2014
012320052014

Papers overview

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2015
2015
Anti-BDCA2 monoclonal antibody inhibits plasmacytoid dendritic cell activation through Fc-dependent and Fc-independent mechanisms
Type I interferons (IFN-I) are implicated in the pathogenesis of systemic lupus erythematosus (SLE). In SLE, immune complexes… (More)
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Highly Cited
2010
Highly Cited
2010
Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9
Recognition of endogenous DNA and RNA by cells expressing TLR7 and TLR9 is an important contributor to the pathogenesis of… (More)
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2010
2010
Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation
Plasmacytoid dendritic cells (pDCs) play a key role in antiviral immunity, but also contribute to the pathogenesis of certain… (More)
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2010
2010
BDCA-2 signaling inhibits TLR-9-agonist-induced plasmacytoid dendritic cell activation and antigen presentation.
Plasmacytoid dendritic cells (PDCs) express Toll-like receptor (TLR) 9, which mediates recognition of microbial DNA during… (More)
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2009
2009
Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: potential implications in inflammatory diseases.
BACKGROUND Increased circulating endothelial microparticles, resulting from vascular endothelium dysfunction, and plasmacytoid… (More)
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2008
2008
Staphylococcus aureus-induced plasmacytoid dendritic cell activation is based on an IgG-mediated memory response.
Type I IFNs represent a major antimicrobial defense mechanism due to their property of enhancing immune responses by priming both… (More)
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2008
2008
Human immunodeficiency virus viremia induces plasmacytoid dendritic cell activation in vivo and diminished alpha interferon production in vitro.
Human immunodeficiency virus type 1 (HIV-1) infection has been associated with perturbations of plasmacytoid dendritic cells (PDC… (More)
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Highly Cited
2006
Highly Cited
2006
IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9.
The Toll-like receptor (TLR) family has important roles in microbial recognition and dendritic cell activation. TLRs 7 and 9 can… (More)
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2006
2006
TLR9 activation is defective in common variable immune deficiency.
Common variable immune deficiency (CVID) is a primary immune deficiency characterized by low levels of serum immune globulins… (More)
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Highly Cited
2005
Highly Cited
2005
Type I interferon dependence of plasmacytoid dendritic cell activation and migration
Differential expression of Toll-like receptor (TLR) by conventional dendritic cells (cDCs) and plasmacytoid DC (pDCs) has been… (More)
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