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pirozadil

Known as: 2,6-pyridinediyldimethylene bis(3,4,5-trimethoxybenzoate) 
A nicotinic acid derivative with antilipidemic activity.
National Institutes of Health

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Pyridines

Papers overview

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1989
1989
Treatment of Diet‐Resistant Polygenic Hypercholesterolaemic Patients with a New Nicotinate Derivative; In Vivo and In Vitro Low Density Lipoprotein Metabolic Studies
Six patients (four women and two men) with mild to moderate hypercholesterolemia, but with no clinical evidence of the disease… 
1989
1989
[Clinical evaluation of pirozadil, administered continuously over four and a half years, in patients with hyperlipoproteinemia type IIa].
With the goal to evaluate the long term efficacy and tolerance of pirozadil, 20 patients with hypercholesterolemia (type II a… 
1989
1989
[Clinical evaluation of pirozadil, administered continuously over four and a half years, in patients with hyperlipoproteinemia type IIa].
Abstract With the goal to evaluate the long term efficacy and tolerance of pirozadil, 20 patients with hypercholesterolemia (type… 
1987
1987
The effect of pirozadil on plasma lipids and lipoproteins in 1185 hyperlipidaemic subjects. Multicentre study in general practice in Spain.
The lipid-lowering agent pirozadil was tested in 1185 hyperlipidaemic subjects during a 2-4 months' intake. Plasma triglycerides… 
1987
1987
Effect of pirozadil on lipids, lipoproteins and apolipoproteins in Japanese with type IIa hyperlipoproteinemia.
Pirozadil (pyridine 2,6-dimethanol-bis(3,4,5-trimethoxybenzoate), Pemix) was administered for 16 weeks at a dose of 1.5 or 2.0 g… 
1986
1986
[Strains and species differences in experimental hyperlipidemia].
Experimental hyperlipidemia was induced in ddY, C57BL, BALB and ICR strain mice and in Wistar rats. By feeding the animals a high… 
1982
1982
[Single-blind study of the efficacy of pirozadil versus alufibrate in the treatment of primary hyperlipoproteinemias].
Pirozadil and alufibrate are compared by a single-blind study over two groups 20 patients with primary hyperlipoproteinemia… 
1982
1982
[Clinical trial of a new drug for the treatment of atherosclerosis: pirozadil (722-D) (author's transl)].
1978
1978
Efficacy of hypolipidemic treatment in inhibition of experimental atherosclerosis: the effect of nicotinic acid and related compounds.
1977
1977
[Effects of pirozadil on metabolic blood flow in brain rabbit (author's transl)].
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