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piposulfan

Known as: 1,4-bis(3-((methylsulfonyl)oxy)-1-oxopropyl)piperazine 
An alkyl sulfonate with potential antineoplastic activity. Piposulfan alkylates DNA, thereby producing DNA interstrand crosslinks and DNA strand… 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

A 20968

Broader (1)

Piperazines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
A SOLID LIPID NANOPARTICLE: AS NOVEL DRUG DELIVERY: AN OVERVIEW
INTRODUCTION Oral route is the most preferred route for drug administration due to greater convenience, less pain, high patient… 
1976
1976
[Novel Bis-sulfonic Acid Esters with Cytostatic Activity (author's transl)].
The introduction of electron-withdrawing groups into the group R of piposulfan analogs R--SO2--O--X--O--SO2--R substantially… 
1971
1971
Effects of piposulfan (Ancyte) on protein and DNA synthesis in Ehrlich ascites carcinoma.
1970
1970
[Treatment of chronic myeloid leukemia and lymphoreticular sarcoma with piposulfan].
1969
1969
Treatment of chronic granulocytic leukemia with piposulfan (NSC-47774).
1968
1968
Effect of piposulfan (NSC-47774) on malignant lymphomas and solid tumors.
1968
1968
Action Du Piposulfan (Ancyte) Dans Les Lymphomes Malins Et Les Tumeurs Solides
SummaryThe effect of a new piperazine derivative, piposulfan or Ancyte, was studied in 21 patients suffering from leukemias and… 
1968
1968
[Effect of piposulfan (ancyte) in malignant lymphomas and solid tumors].
1967
1967
Midwest Cooperative Group evaluation of piposulfan (A‐20968) in cancer
Piposulfan (Ancyte), a methanesulfonate, alkylating derivative of piperazine, was administered to 594 patients with various types… 
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