Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

phosphoribosylaminoimidazolecarboxamide formyltransferase activity

Known as: 5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase activity, 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase activity, AICAR transformylase activity 
Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Abstract 4542: The design, synthesis andin vitroevaluation of selective FR α and β and PCFT substrates with potent GARFTase inhibitory activity as antitumor agents
Three folate transporters, the reduced folate carrier (RFC), folate receptors (FR) and the proton-coupled folate transporter… Expand
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors.
AICAR transformylase (5-aminoimidazole-4-carboxamide ribonucleotide transformylase) is a folate-dependent activity of the… Expand
Is this relevant?
1999
1999
Design, synthesis and evaluation of novel 6-arylsulfonylamino-3-chlorobenzo thiophene-2-carboxyamides Potent, lipophilic inhibitors of 5-aminoimidazole-4-carboxamide ribonucleotide transformylase
 
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE