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phospholamban complex

Known as: cardiac phospholamban complex, cardiac phospholamban complex location, phospholamban complex location 
A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac… 
National Institutes of Health

Related topics

Related topics

3 relations
cardiac PLB complexcardiac PLN complex

Broader (1)

sarcoplasmic reticulum membrane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Colchicine modulates calcium homeostasis and electrical property of HL‐1 cells
Colchicine is a microtubule disruptor that reduces the occurrence of atrial fibrillation (AF) after an operation or ablation… 
2009
2009
On the function of pentameric phospholamban: ion channel or storage form?
Highly Cited
2008
Highly Cited
2008
Phospholamban thiols play a central role in activation of the cardiac muscle sarcoplasmic reticulum calcium pump by nitroxyl.
Nitroxyl (HNO) donated by Angeli's salt activates uptake of Ca(2+) by the cardiac SR Ca(2+) pump (SERCA2a). To determine whether… 
2007
2007
Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes.
Rats with congestive heart failure (CHF) develop ventricular inotropic responsiveness to serotonin (5-HT), mediated through 5-HT… 
2006
2006
Alveolar hypoxia induces left ventricular diastolic dysfunction and reduces phosphorylation of phospholamban in mice.
Chronic obstructive pulmonary disease (COPD) may lead to pulmonary hypertension (PH) and reduced function of the right ventricle… 
2006
2006
Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility.
Transgenic (TG) mice expressing a Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitory peptide targeted to the cardiac… 
2003
2003
Beneficial effects of angiotensin-converting enzyme inhibition on sarcoplasmic reticulum function in the failing heart of the Dahl rat.
Inhibition of angiotensin-converting enzyme (ACE) retards the process of myocardial remodeling and contractile dysfunction that… 
Highly Cited
2002
Highly Cited
2002
Evidence for calcineurin-mediated regulation of SERCA 2a activity in human myocardium.
Compromised SERCA 2a activity is a key malfunction leading to the Ca(2+) cycling alterations in failing human myocardium. SERCA… 
1999
1999
Thyroid hormone control of contraction and the Ca(2+)-ATPase/phospholamban complex in adult rat ventricular myocytes.
Thyroid hormones may have important long-term effects on cellular Ca2+ handling in the heart. We investigated isolated adult rat… 
1998
1998
Pentameric Assembly of Phospholamban Facilitates Inhibition of Cardiac Function in Vivo *
Phospholamban has been proposed to coexist as pentamers and monomers in native sarcoplasmic reticulum membranes. To determine its… 
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