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phospholamban complex

Known as: cardiac phospholamban complex, cardiac phospholamban complex location, phospholamban complex location 
A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac… 
National Institutes of Health

Related topics

Related topics

3 relations
cardiac PLB complexcardiac PLN complex

Broader (1)

sarcoplasmic reticulum membrane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
adenovirusof phospholamban with use of Functional alterations in adult rat myocytes after
2015
2015
Abstract 187: Metformin Increases Degradation of Ubiquitinylated Phospholamban via Autophagy in Cardiomyocytes
Phospholamban (PLN) is an effective inhibitor of the sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) in striated muscles. Here… 
2012
2012
MEK7-JNK1-Akt Signaling Axis Regulates Phospholamban-T17 Phosphorylation and Intracellular Calcium Levels in an Anthrax Model of Acute Diastolic Heart Failure
2009
2009
Valsartan prevents the development of rabbit＇s heart failure by restoring calcium uptake of sarcoplasmic reticulum
content, which is due to reduced SR calcium reuptake by SERCA2a, is responsible for defective systolic function in failing heart… 
2009
2009
Protektive Wirkungen von Trapidil bei Myokardischämie - Vergleichende Untersuchungen an Wildtyp- und Phospholamban-defizienten Mäusen
Fur das Triazolo-Pyrimidin Trapidil (Rocornal®) wurden kardioprotektive Wirkungen in klinischen Studien beschrieben und im… 
Highly Cited
2002
Highly Cited
2002
Evidence for calcineurin-mediated regulation of SERCA 2a activity in human myocardium.
Compromised SERCA 2a activity is a key malfunction leading to the Ca(2+) cycling alterations in failing human myocardium. SERCA… 
Review
1998
Review
1998
Models for the Transmembrane Region of the Phospholamban Pentamer: Which Is Correct? a
ABSTRACT: Phospholamban is a 52‐amino acid protein that assembles into a pentamer in the membranes of the sarcoplasmic reticulum… 
Highly Cited
1996
Highly Cited
1996
Regulation of cardiac sodium-calcium exchanger by beta-adrenergic agonists.
Na+-Ca2+ exchanger and Ca2+ channel are two major sarcolemmal Ca2+-transporting proteins of cardiac myocytes. Although the Ca2… 
1995
1995
The secondary structure of phospholamban: a two-dimensional NMR study.
Phospholamban (PLN) is an intrinsic membrane protein of 52 amino acids which regulates the Ca2+ pump of the sarcoplasmic… 
Review
1980
Review
1980
Role of phosphorylation of the sarcoplasmic reticulum in the cardiac response to catecholamines.
The ability of catecholamines to accelerate relaxation in the myocardium appears to be due in part to phosphorylation of the… 
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