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phosphatidylserine exposure on apoptotic cell surface

Known as: externalization of phosphatidylserine 
A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic… Expand
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

execution phase of apoptosis

Narrower (1)

phospholipid scramblase activity

Papers overview

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2008
2008
Fermented papaya preparation as redox regulator in blood cells of beta-thalassemic mice and patients.
Many aspects of the pathology in beta-hemoglobinopathies (beta-thalassemia and sickle cell anemia) are mediated by oxidative… Expand
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Highly Cited
2007
Highly Cited
2007
Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human…
Nonalcoholic steatohepatitis (NASH) is a progressive fibrotic disease, the pathogenesis of which has not been fully elucidated… Expand
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Highly Cited
2007
Highly Cited
2007
Artemisinin triggers induction of cell-cycle arrest and apoptosis in Leishmania donovani promastigotes.
A major impediment to effective anti-leishmanial chemotherapy is the emergence of drug resistance, especially to sodium antimony… Expand
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Review
2005
Review
2005
Docosahexaenoic acid affects cell signaling by altering lipid rafts.
With 22 carbons and 6 double bonds docosahexaenoic acid (DHA) is the longest and most unsaturated fatty acid commonly found in… Expand
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Highly Cited
2000
Highly Cited
2000
Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139.
Histone H2AX is a ubiquitous member of the H2A histone family that differs from the other H2A histones by the presence of an… Expand
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Highly Cited
1999
Highly Cited
1999
Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.
Release of cytochrome c is important in many forms of apoptosis. Recent studies of CD95 (Fas/APO-1)-induced apoptosis have… Expand
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Highly Cited
1999
Highly Cited
1999
Release of Mitochondrial Cytochrome C in Both Apoptosis and Necrosis Induced by β-Lapachone in Human Carcinoma Cells
BackgroundThere are two fundamental forms of cell death: apoptosis and necrosis. Molecular studies of cell death thus far favor a… Expand
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Highly Cited
1998
Highly Cited
1998
In vivo detection and imaging of phosphatidylserine expression during programmed cell death.
One of the earliest events in programmed cell death is the externalization of phosphatidylserine, a membrane phospholipid… Expand
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Highly Cited
1998
Highly Cited
1998
E4orf4, a Novel Adenovirus Death Factor That Induces p53-independent Apoptosis by a Pathway That Is Not Inhibited by zVAD-fmk
In the absence of E1B, the 289-amino acid product of human adenovirus type 5 13S E1A induces p53-independent apoptosis by a… Expand
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Highly Cited
1997
Highly Cited
1997
Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2.
Apoptosis of Jurkat T cells induced the caspase-mediated proteolytic cleavage of p21-activated kinase 2 (PAK2). Cleavage occurred… Expand
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