FAQ

phosphatidylserine exposure on apoptotic cell surface

Known as: externalization of phosphatidylserine 
A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2018
0102019852018

Related topics

Related topics

2 relations

Broader (1)

execution phase of apoptosis

Narrower (1)

phospholipid scramblase activity

Related mentions per year

Related mentions per year

1985-2018
19801990200020102020
phosphatidylserine exposure on apoptotic cell surface
execution phase of apoptosis
phospholipid scramblase activity

Papers overview

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Highly Cited
2009
Highly Cited
2009
Lipid nanopores can form a stable, ion channel-like conduction pathway in cell membrane.
Cell permeabilization by electric pulses (EPs), or electroporation, has been well established as a tool to indiscriminately… (More)
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2007
2007
MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program.
Activated phagocytes express considerable amounts of MRP8 and MRP14, 2 calcium-binding S100 proteins forming stable heterodimers… (More)
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Highly Cited
2005
Highly Cited
2005
Heat shock prevents alpha-synuclein-induced apoptosis in a yeast model of Parkinson's disease.
We show that human wild-type alpha synuclein (WT alpha-syn), and the inherited mutants A53T or A30P, when expressed in the yeast… (More)
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Highly Cited
2004
Highly Cited
2004
Cryopreservation and thawing is associated with varying extent of activation of apoptotic machinery in subsets of ejaculated human spermatozoa.
We investigated the impact of cryopreservation and thawing on levels of caspases-3, -8, and -9 activity, intact mitochondrial… (More)
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Highly Cited
2002
Highly Cited
2002
A role for oxidative stress in apoptosis: oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosis.
Exposure of phosphatidylserine (PS) on the surface of apoptotic cells has been suggested to serve as an important recognition… (More)
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Highly Cited
1999
Highly Cited
1999
Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.
Release of cytochrome c is important in many forms of apoptosis. Recent studies of CD95 (Fas/APO-1)-induced apoptosis have… (More)
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Highly Cited
1999
Highly Cited
1999
Elevation of mitochondrial transmembrane potential and reactive oxygen intermediate levels are early events and occur independently from activation of caspases in Fas signaling.
Stimulation of the CD95/Fas/Apo-1 receptor leads to apoptosis through activation of the caspase family of cysteine proteases and… (More)
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Highly Cited
1998
Highly Cited
1998
Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells.
Diets high in fat are associated with an increased risk of prostate cancer, although the molecular mechanism is still unknown. We… (More)
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Highly Cited
1998
Highly Cited
1998
E4orf4, a Novel Adenovirus Death Factor That Induces p53-independent Apoptosis by a Pathway That Is Not Inhibited by zVAD-fmk
In the absence of E1B, the 289-amino acid product of human adenovirus type 5 13S E1A induces p53-independent apoptosis by a… (More)
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Highly Cited
1997
Highly Cited
1997
Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2.
Apoptosis of Jurkat T cells induced the caspase-mediated proteolytic cleavage of p21-activated kinase 2 (PAK2). Cleavage occurred… (More)
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