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performance status 4

Known as: Karnofsky 20-30, PS4, Zubrod Performance Status 4 
Completely disabled. Cannot carry on any self-care. Totally confined to bed or chair (Eastern Cooperative Oncology Group)
National Institutes of Health

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Karnofsky Performance Statusperformance status 3

Papers overview

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Highly Cited
2008
Highly Cited
2008
Microscopic Insight into the Sputtering of Thin Polystyrene Films on Ag{111} Induced by Large and Slow Ar Clusters
Molecular dynamics computer simulations were employed to model the bombardment of Ag{111} covered with a monolayer of sec-butyl… 
Review
2006
Review
2006
The next decade of Solar System discovery with Pan-STARRS
Abstract The Panoramic Survey Telescope and Rapid Response System (Pan-STARRS) at the University of Hawaii's Institute for… 
1999
1999
Self heat-shock protein (hsp60) peptide serves in a conjugate vaccine against a lethal pneumococcal infection.
Healthy persons manifest a high frequency of T cells reactive to epitopes of the self 60-kDa heat-shock protein (hsp60) molecule… 
1995
1995
Deficient antipneumococcal polysaccharide responses in HIV-seropositive patients.
In a prospective study, serological responses and opsonic activity towards Streptococcus pneumoniae were measured in 60 HIV… 
1992
1992
The amplifier role of T cells in the human in vitro B cell response to type 4 pneumococcal polysaccharide.
1991
1991
The Human in Vitro Anti‐type 4 Pneumococcal Polysaccharide Antibody Response is Regulated by Suppressor T Cells
In order to study the regulation of the human B‐cell response to T‐cells independent type 2 (TI‐2) antigens, we analysed the role… 
1991
1991
A prepro-TRH connecting peptide (prepro-TRH 160-169) potentiates TRH-induced TSH release from rat perifused pituitaries by stimulating dihydropyridine- and omega-conotoxin-sensitive Ca2+ channels.
The stimulation of TSH secretion by TRH involves the phosphatidylinositol second messenger pathway via activation of… 
1991
1991
Release of pro-thyrotropin-releasing hormone connecting peptides PS4 and PS5 from perifused rat hypothalamic slices
Highly Cited
1990
Highly Cited
1990
Processing of thyrotropin-releasing hormone prohormone (pro-TRH) generates a biologically active peptide, prepro-TRH-(160-169), which regulates TRH-induced thyrotropin secretion.
Rat thyrotropin-releasing hormone (TRH) prohormone contains five copies of the TRH progenitor sequence Gln-His-Pro-Gly linked… 
1988
1988
8-Mercaptoguanosine overcomes unresponsiveness of human neonatal B cells to polysaccharide antigens.
We have shown previously that pneumococcal polysaccharides behave as human T cell-independent type 2 Ag. When cultured in vitro… 
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