FAQ

performance status 2

Known as: Karnofsky 60-70, PS2, Zubrod Performance Status 2 
Ambulatory and capable of all self-care but unable to carry out any work activities. Up and about more than 50% of waking hours (Eastern Cooperative… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2016
010203019782016

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Related topics

1 relation
Karnofsky Performance Status

Related mentions per year

Related mentions per year

1948-2018
19401960198020002020
performance status 2
Karnofsky Performance Status

Papers overview

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2009
2009
Pooled safety and efficacy analysis examining the effect of performance status on outcomes in nine first-line treatment trials using individual data from patients with metastatic colorectal cancer.
PURPOSE Performance status (PS) is a prognostic factor in patients with metastatic colorectal cancer. Clinical trials typically… (More)
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2005
2005
Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases.
Gamma-secretase depends on presence of presenilins (PS), Nct, Aph-1, and PEN-2 within a core complex. This endoproteolytic… (More)
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2005
2005
APOE and other loci affect age-at-onset in Alzheimer's disease families with PS2 mutation.
Several kindreds of Volga German (VG) ancestry have a single PS2 mutation that causes an autosomal dominant form of Alzheimer's… (More)
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2002
2002
KAZHDAN-LUSZTIG POLYNOMIALS AND CHARACTER FORMULAE FOR THE LIE SUPERALGEBRA q(n)
  • JONATHAN BRUNDAN
  • 2002
The problem of computing the characters of the finite dimensional irreducible representations for the classical Lie superalgebras… (More)
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2001
2001
Detection of chlorophyll d' and pheophytin a in a chlorophyll d-dominating oxygenic photosynthetic prokaryote Acaryochloris marina.
 
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2000
2000
The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation.
The discovery that a deficiency of presenilin 1 (PS1) decreases the production of amyloid beta-protein (Abeta) identified the… (More)
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Highly Cited
1999
Highly Cited
1999
Mice lacking both presenilin genes exhibit early embryonic patterning defects.
Genetic studies in worms, flies, and humans have implicated the presenilins in the regulation of the Notch signaling pathway and… (More)
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1999
1999
S-layer protein production by Corynebacterium strains is dependent on the carbon source.
Three strains of Corynebacterium producing various amounts of PS2 S-layer protein were studied. For all strains, more PS2 was… (More)
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1998
1998
Stable association of presenilin derivatives and absence of presenilin interactions with APP.
Mutations in two related genes, presenilin 1 and 2 presenilin 2 (PS1 and PS2), cosegregate with Alzheimer's disease. PS1 and PS2… (More)
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1998
1998
Genetic analysis of the Drosophila alphaPS2 integrin subunit reveals discrete adhesive, morphogenetic and sarcomeric functions.
The integrin family of cell surface receptors mediates cell-substrate and cell-to-cell adhesion and transmits intracellular… (More)
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