palomid 529
National Institutes of Health
Papers overview
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Idiopathic pulmonary fibrosis is a progressive and deadly disorder with very few therapeutic options. Palomid 529 (8‐(1…
BackgroundLiver kinase B1 (LKB1) loss by gene mutation, loss of heterozygosity, and promoter methylation rarely occurs in…
BackgroundRecent evidence suggests that neovascular age-related macular degeneration (AMD) may have an immune mediated component…
Palomid 529, a novel dual mTORC1/2 inhibitor has displayed interesting activities in experimental models and is a candidate for…
One of the major obstacles in the treatment of hormone-refractory prostate cancer (HRPC) is the development of chemo-resistant…
Palomid 529 (P529) is a small molecule drug created through three generations of computational design. P529 is an anti-tumor…
Radiotherapy (RT) is a common treatment for localised prostate cancer, but can cause important side effects. The therapeutic…
PURPOSE
To test the effect of Palomid 529, an inhibitor of the Akt/mTOR pathway, on Müller cell proliferation, subretinal glial…
It has become clear that the phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway is central for…