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palladium-bacteriopheophorbide

Known as: Pd-Bpheid, Pd-bacteriopheophorbide 
A novel palladium-substituted bacteriochlorophyll derivative and photosensitizer with potential antitumor activity. Upon administration, inactive… Expand
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Bacteriochlorophylls

Narrower (2)

TOOKADWST 09

Papers overview

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Highly Cited
2007
Highly Cited
2007
Vascular targeted photodynamic therapy with palladium-bacteriopheophorbide photosensitizer for recurrent prostate cancer following definitive radiation therapy: assessment of safety and treatment…
PURPOSE Tookad is a novel intravascular photosensitizer. When activated by 763 nm light, it destroys tumors by damaging their… Expand
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2005
2005
In vitro activity of C-20 methyltransferase, BchU, involved in bacteriochlorophyll c biosynthetic pathway in green sulfur bacteria.
The activity of a methyltransferase, BchU, which catalyzes methylation at the C-20 position of chlorin ring in the biosynthetic… Expand
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2004
2004
Perfusion, oxygenation status and growth of experimental tumors upon photodynamic therapy with Pd-bacteriopheophorbide.
The aim of this study was to assess the anti-tumor effect of photodynamic therapy (PDT) using a novel bacteriochlorophyll… Expand
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2004
2004
Determination of the in vivo pharmacokinetics of palladium-bacteriopheophorbide (WST09) in EMT6 tumour-bearing Balb/c mice using graphite furnace atomic absorption spectroscopy.
Palladium-bacteriopheophorbide (WST09), a novel bacteriochlorophyll derivative, is currently being investigated for use as a… Expand
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Highly Cited
2003
Highly Cited
2003
Monitoring photodynamic therapy of solid tumors online by BOLD-contrast MRI
Antivascular photodynamic therapy (PDT) of tumors with palladium-bacteriopheophorbide (TOOKAD) relies on in situ… Expand
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2003
2003
Bypass of tumor drug resistance by antivascular therapy.
Multidrug resistance (MDR) presents a major obstacle for the successful chemotherapy of cancer. Its emergence during chemotherapy… Expand
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2003
2003
Evaluation of the Photosensitizer Tookad® for Photodynamic Therapy on the Syrian Golden Hamster Cheek Pouch Model: Light Dose, Drug Dose and Drug–light Interval Effects¶
Abstract We have evaluated the efficacy of the new photosensitizer (PS) Tookad® in photodynamic therapy (PDT) in vivo. This PS is… Expand
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Highly Cited
2002
Highly Cited
2002
Preclinical Studies in Normal Canine Prostate of a Novel Palladium-Bacteriopheophorbide (WST09) Photosensitizer for Photodynamic Therapy of Prostate Cancer¶
Abstract Photodynamic therapy (PDT) uses light to activate a photosensitizer to achieve localized tumor control. In this study… Expand
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Highly Cited
2002
Highly Cited
2002
Local photodynamic therapy (PDT) of rat C6 glioma xenografts with Pd-bacteriopheophorbide leads to decreased metastases and increase of animal cure compared with surgery.
Photodynamic therapy (PDT), locally applied to solid C6 rat glioma tumors in the foot of CD1 nude mice, eradicated the primary… Expand
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1994
1994
Subcellular storage compartments of bacteriopheophorbide sensitizers
Fluorescence colocalization with the Golgi specific stain, NBD-ceramide, and the mitochondrial localizing stain, Rhodamine 123… Expand
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