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palladium-bacteriopheophorbide

Known as: Pd-Bpheid, Pd-bacteriopheophorbide 
A novel palladium-substituted bacteriochlorophyll derivative and photosensitizer with potential antitumor activity. Upon administration, inactive… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
PURPOSE Tookad is a novel intravascular photosensitizer. When activated by 763 nm light, it destroys tumors by damaging their… Expand
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2005
2005
The activity of a methyltransferase, BchU, which catalyzes methylation at the C‐20 position of chlorin ring in the biosynthetic… Expand
2004
2004
The aim of this study was to assess the anti-tumor effect of photodynamic therapy (PDT) using a novel bacteriochlorophyll… Expand
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2004
2004
Palladium-bacteriopheophorbide (WST09), a novel bacteriochlorophyll derivative, is currently being investigated for use as a… Expand
Highly Cited
2003
Highly Cited
2003
Antivascular photodynamic therapy (PDT) of tumors with palladium-bacteriopheophorbide (TOOKAD) relies on in situ… Expand
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2003
2003
Multidrug resistance (MDR) presents a major obstacle for the successful chemotherapy of cancer. Its emergence during chemotherapy… Expand
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2003
2003
Abstract We have evaluated the efficacy of the new photosensitizer (PS) Tookad® in photodynamic therapy (PDT) in vivo. This PS is… Expand
2003
2003
Photodynamic therapy (PDT) mediated with vascular acting photosensitizer pd-bacteriopheophorbide (Tookad), is investigated as an… Expand
Highly Cited
2002
Highly Cited
2002
Photodynamic therapy (PDT), locally applied to solid C6 rat glioma tumors in the foot of CD1 nude mice, eradicated the primary… Expand
Highly Cited
2002
Highly Cited
2002
Abstract Photodynamic therapy (PDT) uses light to activate a photosensitizer to achieve localized tumor control. In this study… Expand