pafenolol
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
SummaryPafenolol, a new selective adrenergic beta1-blocking agent, has been tested for the first time in 6 hypertensive patients…
SummaryPafenolol, a new β1-adrenoceptor antagonist, has been shown in animal studies to be more selective for the β1-adrenoceptor…
OBJECTIVE
The main aim of this study was to provide a simple, pharmacokinetic rationale for great similarity in the extent (Fab…
The elimination of [3H]pafenolol and metabolites was investigated in fasted and fed rats. Separate groups received intravenous…
The pharmacokinetics of pafenolol were studied in eight young healthy individuals. The doses were 10 mg iv and 40 mg orally. Each…
The pharmacokinetics of pafenolol, a highly selective beta 1-adrenoceptor antagonist, have been studied in starved and unstarved…
The pharmacokinetics of pafenolol were evaluated in 12 healthy subjects after administration of three single IV doses (5, 10, and…
Summary: The antihypertensive effect of pafenolol, a new beta1-selective adrenoceptor blocker without intrinsic sympathomimetic…
To test the usefulness of noninvasive ambulatory 24-hour blood pressure recording, the Del Mar Avionics system was used in a…
Summary: We characterized the β-adrenoceptor subtype in isolated ring preparations of small intramyocardial flow-regulating…