Skip to search formSkip to main contentSkip to account menu

pafenolol

National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Propanolamines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
A comprehensive account on the role of efflux transporters in the gastrointestinal absorption of 13 commonly used substrate drugs in humans.
BACKGROUND The potential absorption-limiting effect of intestinal efflux transporters such as P-glycoprotein (P-gp) has been well… 
2000
2000
Similarity in the linear and non-linear oral absorption of drugs between human and rat.
OBJECTIVE The main aim of this study was to provide a simple, pharmacokinetic rationale for great similarity in the extent (Fab… 
1993
1993
Dose-Dependent Intestinal Absorption and Significant Intestinal Excretion (Exsorption) of the β-Blocker Pafenolol in the Rat
The elimination of [3H]pafenolol and metabolites was investigated in fasted and fed rats. Separate groups received intravenous… 
1992
1992
Mediation of contraction and relaxation by alpha- and beta-adrenoceptors in the ureterovesical junction of the sheep.
1990
1990
Pharmacokinetics of a Single Intravenous and Oral Dose of Pafenolol—a Beta1Adrenoceptor Antagonist with Atypical Absorption and Disposition Properties—in Man
The pharmacokinetics of pafenolol were studied in eight young healthy individuals. The doses were 10 mg iv and 40 mg orally. Each… 
1990
1990
Pharmacokinetics of pafenolol after i.v. and oral administration of three separate doses of different strength to man.
The pharmacokinetics of pafenolol were evaluated in 12 healthy subjects after administration of three single IV doses (5, 10, and… 
1990
1990
Pharmacokinetics of pafenolol in the rat: a suitable model for studying absorption mechanisms of a drug exhibiting unusual absorption properties in man.
The pharmacokinetics of pafenolol, a highly selective beta 1-adrenoceptor antagonist, have been studied in starved and unstarved… 
1986
1986
β-Adrenergic control of motility in the rat colon. II. Proportions of β1- and β2-adrenoceptors identified with 125I-(−)pindolol binding
1985
1985
Monitoring 24-hour blood pressure in a drug trial. Evaluation of a noninvasive device.
To test the usefulness of noninvasive ambulatory 24-hour blood pressure recording, the Del Mar Avionics system was used in a… 
1985
1985
Characterization of β-Adrenoceptor Subtype in Isolated Ring Preparations of Intramural Rat Coronary Small Arteries
Summary: We characterized the β-adrenoceptor subtype in isolated ring preparations of small intramyocardial flow-regulating… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)