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pafenolol

 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Pafenolol is a β-blocker with unusual oral absorption properties. The blood concentration–time profile exhibits two peaks, and… Expand
2004
2004
The gastrointestinal absorption characteristics of pafenolol following oral administration as a solution in man and rat has… Expand
2004
2004
The elimination of [3H]pafenolol and metabolites was investigated in fasted and fed rats. Separate groups received intravenous… Expand
2004
2004
The pharmacokinetics of pafenolol were studied in eight young healthy individuals. The doses were 10 mg iv and 40 mg orally. Each… Expand
Highly Cited
2001
Highly Cited
2001
BACKGROUND The potential absorption-limiting effect of intestinal efflux transporters such as P-glycoprotein (P-gp) has been well… Expand
Highly Cited
1993
Highly Cited
1993
1 The transepithelial transport of the β‐adrenoceptor blocking drug, celiprolol, was investigated in monolayers of the well… Expand
1993
1993
Pafenolol is a beta 1-adrenoreceptor antagonist exhibiting some interesting oral absorption properties in both rat and humans… Expand
Highly Cited
1992
Highly Cited
1992
1 We have studied the effects of α‐ and β‐adrenoceptor agonists and antagonists on both phasic peristaltic activity and basal… Expand
1987
1987
The myocardial potassium uptake during intracoronary isoproterenol stimulation was characterized in 12 anesthetized pigs. The… Expand
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1983
1983
Pafenolol, a new β1‐adrenoceptor antagonist, has been shown in animals to be more selective for β1‐adrenoceptors than metoprolol… Expand