paclitaxel metabolic process

Known as: paclitaxel metabolism 
The chemical reactions and pathways involving paclitaxel, an alkaloid compound used as an anticancer treatment. [CHEBI:45863, GOC:jl]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The cytochrome P450 (CYP) 2C8*3 allele is associated with reduced metabolic activity of paclitaxel. This study was aimed to… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2015
2015
Desloratadine (Clarinex), the major active metabolite of loratadine (Claritin), is a nonsedating long-lasting antihistamine that… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
2014
2014
e250 www.thelancet.com/oncology Vol 15 June 2014 with 7% in MITO-7, and grade 3–4 anaemia occurred in 44% of patients in NOVEL… (More)
Is this relevant?
2013
2013
Paclitaxel is avidly transported by P-glycoprotein (P-gp/MDR1/ABCB1). This results in low oral bioavailability, which can be… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2011
2011
The formulation vehicle Cremophor EL has previously been shown to affect paclitaxel kinetics, but it is not known whether it also… (More)
  • table 3
Is this relevant?
2006
2006
OBJECTIVE Paclitaxel is one of the most important anticancer drugs for the treatment of various tumors such as non-small cell… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
By sequencing genomic DNA from 73 established cell lines derived from Japanese individuals, we detected 9 single nucleotide… (More)
Is this relevant?
Review
1997
Review
1997
Paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) has been demonstrated to be an active anticancer agent, including… (More)
Is this relevant?
1995
1995
Histamine-2 receptor antagonists (H2RAs) are principal components of the premedication regimen used to prevent major… (More)
  • figure 1
  • table 1
  • figure 2
Is this relevant?
1995
1995
 Histamine-2 receptor antagonists (H2RAs) are principal components of the premedication regimen used to prevent major… (More)
Is this relevant?