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ottelione B

National Institutes of Health

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Cyclohexanones

Papers overview

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2008
2008
Synthesis of the potent anticancer agents ottelione A and ottelione B in both racemic and natural optically pure forms.
The powerful antitumor agents ottelione A and B were synthesized in racemic form by a method that relies on selective ring… 
2007
2007
Enantioselective total synthesis of (+)-ottelione A, (-)-ottelione B, (+)-3-epi-ottelione A and preliminary evaluation of their antitumor activity.
Enantioselective total synthesis of (+)-ottelione A (1) and (-)-ottelione B (2), novel and potent antitumor agents from a… 
2003
2003
Enantioselective total syntheses of (+)- and (−)-ottelione A and (+)- and (−)-ottelione B. Absolute configuration of the novel, biologically active natural products
2002
2002
Synthesis of the bicyclic dienone core of the antitumor agent ottelione B.
The intramolecular Diels-Alder adduct 12 was converted via dimesylate 20 into dienone 7, which represents the unusual, and… 
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