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orotidylic acid

Known as: 5-(dihydrogen phosphate)orotidine, orotidine 5'-monophosphate 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Uridine Monophosphate
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
A role for flexible loops in enzyme catalysis.
Highly Cited
2000
Highly Cited
2000
Electrostatic stress in catalysis: structure and mechanism of the enzyme orotidine monophosphate decarboxylase.
Orotidine 5'-monophosphate decarboxylase catalyzes the conversion of orotidine 5'-monophosphate to uridine 5'-monophosphate, the… 
Highly Cited
2000
Highly Cited
2000
Anatomy of a proficient enzyme: the structure of orotidine 5'-monophosphate decarboxylase in the presence and absence of a potential transition state analog.
Orotidine 5'-phosphate decarboxylase produces the largest rate enhancement that has been reported for any enzyme. The crystal… 
Highly Cited
2000
Highly Cited
2000
Remarkable rate enhancement of orotidine 5'-monophosphate decarboxylase is due to transition-state stabilization rather than to ground-state destabilization.
The remarkable rate enhancement of orotidine 5'-phosphate decarboxylase (ODCase) has been attributed to ground-state… 
Highly Cited
2000
Highly Cited
2000
The crystal structure and mechanism of orotidine 5'-monophosphate decarboxylase.
The crystal structure of Bacillus subtilis orotidine 5'-monophosphate (OMP) decarboxylase with bound uridine 5'-monophosphate has… 
2000
2000
Determination of the mechanism of orotidine 5'-monophosphate decarboxylase by isotope effects.
Orotidine 5'-monophosphate shows a (15)N isotope effect of 1.0036 at N-1 for decarboxylation catalyzed by orotidine 5… 
Highly Cited
1997
Highly Cited
1997
A proficient enzyme revisited: the predicted mechanism for orotidine monophosphate decarboxylase.
A mechanism is proposed to explain the activity of orotidine 5'-monophosphate decarboxylase (ODCase). This enzyme is the one of… 
Highly Cited
1975
Highly Cited
1975
Studies on a pyrimidine phosphoribosyltransferase from murine leukemia P1534J. Partial purification, substrate specificity, and evidence for its existence as a bifunctional complex with orotidine 5…
Review
1970
Review
1970
Regulation of pyrimidine and arginine biosynthesis in mammals.
  • M. E. Jones
  • Advances in Enzyme Regulation
  • 1970
  • Corpus ID: 20968844
Highly Cited
1959
Highly Cited
1959
The biochemical activity of 6-azauridine: interference with pyrimidine metabolism in transplantable mouse tumors.
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