orotidylic acid

Known as: 5-(dihydrogen phosphate)orotidine, orotidine 5'-monophosphate 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2017
0246819732017

Papers overview

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2011
2011
The efficacy of most marketed antimalarial drugs has been compromised by evolution of parasite resistance, underscoring an urgent… (More)
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2011
2011
The final two steps of de novo uridine 5'-monophosphate (UMP) biosynthesis are catalyzed by orotate phosphoribosyltransferase… (More)
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2005
2005
We report that the binding of phosphite dianion to orotidine 5'-monophosphate decarboxylase (OMPDC) results in an 80 000-fold… (More)
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Highly Cited
2004
Highly Cited
2004
Uridine auxotrophy, based on disruption of both URA3 alleles in diploid Candida albicans strain SC5314, has been widely used to… (More)
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2000
2000
Orotidine 5'-monophosphate decarboxylase catalyzes the conversion of orotidine 5'-monophosphate to uridine 5'-monophosphate, the… (More)
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2000
2000
Orotidine 5'-phosphate decarboxylase produces the largest rate enhancement that has been reported for any enzyme. The crystal… (More)
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2000
2000
The crystal structure of Bacillus subtilis orotidine 5'-monophosphate (OMP) decarboxylase with bound uridine 5'-monophosphate has… (More)
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Highly Cited
1998
Highly Cited
1998
The ura-blaster technique for the disruption of Candida albicans genes has been employed in a number of studies to identify… (More)
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1996
1996
Orotate phosphoribosyltransferase (OPRTase) is involved in the biosynthesis of pyrimidine nucleotides. Alpha-D-ribosyldiphosphate… (More)
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1975
1975
A pyrimidine phosphoribosyltransferase, previously shown to utilize 5-fluorouracil and possibly also uracil and orotate (Reyes, P… (More)
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