Skip to search formSkip to main contentSkip to account menu

orotidylic acid

Known as: 5-(dihydrogen phosphate)orotidine, orotidine 5'-monophosphate 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Uridine Monophosphate
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds.
Review
2003
Review
2003
Catalysis by enzyme conformational change as illustrated by orotidine 5'-monophosphate decarboxylase.
2002
2002
Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography.
The crystal structures of orotidine 5'-monophosphate decarboxylases from four different sources have been published recently… 
2000
2000
Determination of the mechanism of orotidine 5'-monophosphate decarboxylase by isotope effects.
Orotidine 5'-monophosphate shows a (15)N isotope effect of 1.0036 at N-1 for decarboxylation catalyzed by orotidine 5… 
Highly Cited
1997
Highly Cited
1997
A proficient enzyme revisited: the predicted mechanism for orotidine monophosphate decarboxylase.
A mechanism is proposed to explain the activity of orotidine 5'-monophosphate decarboxylase (ODCase). This enzyme is the one of… 
Highly Cited
1996
Highly Cited
1996
A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase.
Orotate phosphoribosyltransferase (OPRTase) is involved in the biosynthesis of pyrimidine nucleotides. Alpha-D-ribosyldiphosphate… 
Highly Cited
1995
Highly Cited
1995
The crystal structure of the orotate phosphoribosyltransferase complexed with orotate and alpha-D-5-phosphoribosyl-1-pyrophosphate.
The three-dimensional structure of Salmonella typhimurium orotate phosphoribosyltransferase (OPRTase) in complex with the ribose… 
Highly Cited
1993
Highly Cited
1993
5-Benzylbarbituric acid derivatives, potent and specific inhibitors of uridine phosphorylase.
Highly Cited
1975
Highly Cited
1975
Studies on a pyrimidine phosphoribosyltransferase from murine leukemia P1534J. Partial purification, substrate specificity, and evidence for its existence as a bifunctional complex with orotidine 5…
Highly Cited
1971
Highly Cited
1971
Regulation of pyrimidine and arginine biosynthesis in mammals
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)