Skip to search formSkip to main contentSkip to account menu

ophiocordin

Known as: Benzoic acid, 4-(2-(((hexahydro-4-((4-hydroxybenzoyl)oxy)-1H-azepin-3-yl)amino)carbonyl)-6-hydroxybenzoyl)-3,5-dihydroxy-, balanol 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Antibiotics, AntifungalAzepinesHydroxybenzoates

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Stereoselective synthesis of hydroxylated 3-aminoazepanes using a multi-bond forming, three-step tandem process.
A multi-bond forming, three-step tandem process involving a palladium(II)-catalysed Overman rearrangement and a ring closing… 
2010
2010
Recent chemoenzymatic total syntheses of natural and unnatural products: Codeine, balanol, pancratistatin, and oseltamivir
Presented here is a short summary of the recent accomplishments in total synthesis in our laboratories. In particular, recent… 
Review
2008
Review
2008
The Protein kinase inhibitor balanol: structure-activity relationships and structure-based computational studies.
Balanol, a fungal metabolite, is a potent ATP-competitive inhibitor of Protein Kinase C (PKC) and Protein Kinase A (PKA… 
2004
2004
Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit.
The protein kinase family is a prime target for therapeutic agents, since unregulated protein kinase activities are linked to… 
2002
2002
Synthesis and protein kinase inhibitory activity of balanol analogues with modified benzophenone subunits.
A series of analogues of the protein kinase C (PKC) inhibitory natural product balanol which bear modified benzophenone subunits… 
Review
2002
Review
2002
Designing specific protein kinase inhibitors: insights from computer simulations and comparative sequence/structure analysis.
2000
2000
Synthesis of the benzophenone fragment of balanol via an intramolecular cyclization event.
Studies are reported on the use of either a 7-exo radical cyclization or an intramolecular Heck reaction as the key step for the… 
1999
1999
Asymmetric synthesis of the balanol heterocycle via a palladium-mediated epimerization and olefin metathesis.
[formula: see text] The enantioselective formal synthesis of balanol, a potent protein kinase C inhibitor, was accomplished from… 
1997
1997
Synthesis and protein kinase C inhibitory activities of balanol analogs with replacement of the perhydroazepine moiety.
Balanol is a potent protein kinase C (PKC) inhibitor that is structurally composed of a benzophenone diacid, a 4-hydroxybenzamide… 
1997
1997
Synthesis and protein kinase C inhibitory activities of balanol analogues with modification of 4-hydroxybenzamido moiety.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)