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ophiocordin

Known as: Benzoic acid, 4-(2-(((hexahydro-4-((4-hydroxybenzoyl)oxy)-1H-azepin-3-yl)amino)carbonyl)-6-hydroxybenzoyl)-3,5-dihydroxy-, balanol 
 
National Institutes of Health

Papers overview

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Review
2012
Review
2012
G protein-coupled receptor (GPCR) kinases (GRKs) are best known for their role in homologous desensitization of GPCRs. GRKs… Expand
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Highly Cited
2011
Highly Cited
2011
G protein-coupled receptors (GPCRs) are key regulators of cell physiology and control processes ranging from glucose homeostasis… Expand
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Highly Cited
2010
Highly Cited
2010
G protein-coupled receptor kinase 2 (GRK2) is a pharmaceutical target for the treatment of cardiovascular diseases such as… Expand
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Highly Cited
2007
Highly Cited
2007
Conformational changes of biological macromolecules when binding with ligands have long been observed and remain a challenge for… Expand
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Highly Cited
2005
Highly Cited
2005
Even if the structure of a receptor has been determined experimentally, it may not be a conformation to which a ligand would bind… Expand
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2004
2004
An unknown antibiotic, ophiocordin, C21H22N2O8, MW: 430, was isolated from submerged cultures of Cordyceps ophioglossoides… Expand
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2004
2004
The protein kinase family is a prime target for therapeutic agents, since unregulated protein kinase activities are linked to… Expand
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Highly Cited
1999
Highly Cited
1999
Protein kinases are essential for the regulation of cellular growth and metabolism. Since their dysfunction leads to debilitating… Expand
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1999
1999
[formula: see text] The enantioselective formal synthesis of balanol, a potent protein kinase C inhibitor, was accomplished from… Expand
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1995
1995
BACKGROUND The protein kinase C (PKC) family of serine/threonine-specific protein kinases is involved in many cellular processes… Expand
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