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ophiocordin

Known as: Benzoic acid, 4-(2-(((hexahydro-4-((4-hydroxybenzoyl)oxy)-1H-azepin-3-yl)amino)carbonyl)-6-hydroxybenzoyl)-3,5-dihydroxy-, balanol 
National Institutes of Health

Papers overview

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Review
2012
Review
2012
G protein-coupled receptor (GPCR) kinases (GRKs) are best known for their role in homologous desensitization of GPCRs. GRKs… Expand
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Highly Cited
2011
Highly Cited
2011
G protein-coupled receptors (GPCRs) are key regulators of cell physiology and control processes ranging from glucose homeostasis… Expand
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Highly Cited
2010
Highly Cited
2010
G protein-coupled receptor kinase 2 (GRK2) is a pharmaceutical target for the treatment of cardiovascular diseases such as… Expand
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Highly Cited
2007
Highly Cited
2007
Conformational changes of biological macromolecules when binding with ligands have long been observed and remain a challenge for… Expand
2004
2004
An unknown antibiotic, ophiocordin, C21H22N2O8, MW: 430, was isolated from submerged cultures of Cordyceps ophioglossoides… Expand
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2004
2004
The protein kinase family is a prime target for therapeutic agents, since unregulated protein kinase activities are linked to… Expand
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2001
2001
Protein kinases are important targets for designing therapeutic drugs. This paper illustrates a computational approach to extend… Expand
Review
1999
Review
1999
Protein kinase C (PKC) is a family of enzymes that play a ubiquitous role in intracellular signal transduction. Our understanding… Expand
Highly Cited
1999
Highly Cited
1999
Protein kinases are essential for the regulation of cellular growth and metabolism. Since their dysfunction leads to debilitating… Expand
1999
1999
[formula: see text] The enantioselective formal synthesis of balanol, a potent protein kinase C inhibitor, was accomplished from… Expand