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omadacycline
Known as:
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-9-{[(2,2-dimethylpropyl)amino]methyl}- 3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- carboxamide
National Institutes of Health
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Omadacycline:Susc:Pt:Isolate:OrdQn:MIC
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Surveillance of Omadacycline Activity Tested against Clinical Isolates from the United States and Europe: Report from the SENTRY Antimicrobial Surveillance Program, 2016 to 2018
M. Pfaller
,
M. Huband
,
D. Shortridge
,
R. Flamm
Antimicrobial Agents and Chemotherapy
2020
Corpus ID: 211193727
Omadacycline is a broad-spectrum aminomethylcycline approved in October 2018 by the U.S. Food and Drug Administration for…
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Highly Cited
2019
Highly Cited
2019
In Vitro Activities of Omadacycline against Rapidly Growing Mycobacteria
C. Shoen
,
David Benaroch
,
Mary R Sklaney
,
M. Cynamon
Antimicrobial Agents and Chemotherapy
2019
Corpus ID: 75140698
The in vitro activity of omadacycline, a new tetracycline derivative, was evaluated against isolates of Mycobacterium abscessus…
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Highly Cited
2019
Highly Cited
2019
In Vitro Activity of New Tetracycline Analogs Omadacycline and Eravacycline against Drug-Resistant Clinical Isolates of Mycobacterium abscessus
A. Kaushik
,
Nicole C. Ammerman
,
O. Martins
,
N. Parrish
,
E. Nuermberger
Antimicrobial Agents and Chemotherapy
2019
Corpus ID: 104295262
Tigecycline is used in multidrug regimens for salvage therapy of Mycobacterium abscessus infections but is often poorly tolerated…
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Review
2019
Review
2019
Microbiology and Preclinical Review of Omadacycline
J. Karlowsky
,
J. Steenbergen
,
G. Zhanel
Clinical Infectious Diseases
2019
Corpus ID: 199056731
Abstract Omadacycline is a novel aminomethylcycline antimicrobial and semisynthetic derivative of tetracycline. In vitro…
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2019
2019
Omadacycline as a promising new agent for the treatment of infections with Mycobacterium abscessus
H. Bax
,
C. D. de Vogel
,
J. Mouton
,
J. D. de Steenwinkel
Journal of Antimicrobial Chemotherapy
2019
Corpus ID: 195355398
Abstract Background Despite intensive treatment regimens, the outcome of Mycobacterium abscessus infections is extremely poor and…
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2019
2019
Omadacycline for Acute Bacterial Skin and Skin Structure Infections
F. Abrahamian
,
G. Sakoulas
,
+5 authors
P. Mcgovern
Clinical Infectious Diseases
2019
Corpus ID: 199055356
Abstract Background Within the last decade, methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a frequent cause of…
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Review
2017
Review
2017
Antibiotics in late clinical development
P. Fernandes
,
E. Martens
Biochemical Pharmacology
2017
Corpus ID: 38934367
Review
2017
Review
2017
New and improved? A review of novel antibiotics for Gram-positive bacteria.
Mohamed Abbas
,
Mical Paul
,
Mical Paul
,
Angela Huttner
Clinical Microbiology and Infection
2017
Corpus ID: 36791967
2017
2017
Pharmacokinetics and Safety of Omadacycline in Subjects with Impaired Renal Function
J. Berg
,
E. Tzanis
,
+4 authors
S. Villano
Antimicrobial Agents and Chemotherapy
2017
Corpus ID: 20226844
ABSTRACT Many antibiotics require dose adjustments in patients with renal impairment and/or in those undergoing hemodialysis…
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Highly Cited
2013
Highly Cited
2013
In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline
A. Macone
,
B. Caruso
,
+5 authors
S. Levy
Antimicrobial Agents and Chemotherapy
2013
Corpus ID: 41567733
ABSTRACT Omadacycline is the first intravenous and oral 9-aminomethylcycline in clinical development for use against multiple…
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