olpadronate

PURPOSE Metastatic bone disease is one of the major causes of morbidity and mortality in prostate cancer patients… Expand

BACKGROUND Periodontitis is characterized by gingival inflammation, periodontal pocket formation, and bacterial plaque that lead… Expand

BACKGROUND Non-randomised studies have suggested beneficial effects of bisphosphonates in osteogenesis imperfecta. We assessed… Expand

Bisphosphonates (BPs) are pyrophosphate analogues in which the oxygen in P-O-P has been replaced by a carbon, resulting in a… Expand

Glucocorticoid-induced osteoporosis may be due, in part, to increased apoptosis of osteocytes and osteoblasts, and… Expand

Bisphosphonates (Bps), inhibitors of osteoclastic bone resorption, are used in the treatment of skeletal disorders. Recent… Expand

Prostate cancer is predominantly associated with osteoblastic bone metastases, but an increase in bone resorption has been… Expand

Abstract Osteoporosis is an important feature of osteogenesis imperfecta (OI). So far, no effective medical treatment is… Expand

Bisphosphonates are used with increasing frequency in the management of skeletal complications in patients with breast cancer. In… Expand

As part of a safety-assessment study, doses of 8, 40, and 200 mg/kg per day, 6 days per week, of sodium olpadronate (dimethyl-APD… Expand