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nordy

National Institutes of Health

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Masoprocol
analogs & derivatives

Papers overview

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2016
2016
Anti-tumor effect of ultrasound-induced Nordy-loaded microbubbles destruction
Abstract Background: Synthesized dl-Nordihydroguaiaretic acid (dl-NGDA or “Nordy”) can inhibit the growth of malignant human… 
2011
2011
An Inhibitor of Arachidonate 5-Lipoxygenase, Nordy, Induces Differentiation and Inhibits Self-Renewal of Glioma Stem-Like Cells
Recent progress in cancer biology indicates that eradication of cancer stem cells (CSCs) is essential for more effective cancer… 
2008
2008
Unique proteomic features induced by a potential antiglioma agent, Nordy (dl‐nordihydroguaiaretic acid), in glioma cells
Nordy is a chirally synthesized compound of a natural lipoxygenase inhibitor nordihydroguaiaretic acid. In this study, we found… 
2008
2008
The differentiation-inducing effect of Nordy on HPV-16 subgenes-immortalized human endocervical cells H8
The lipoxygenase inhibitor nordihydroguaiaretic acid, a natural product purified from Larrea divaricata and Guaiacum officinale… 
2008
2008
[Effect of nordy on the function of endothelial progenitor cells from human umbilical cord blood induced by vascular endothelial growth factor].
This study is to investigate whether the synthesized chiral compound Nordy has influence on the function of endothelial… 
2007
2007
The anti-cancer compound Nordy inhibits CXCR4-mediated production of IL-8 and VEGF by malignant human glioma cells
The chemokine receptor CXCR4 plays an important role in tumor growth, angiogenesis and metastasis. Our previous studies showed… 
Highly Cited
2007
Highly Cited
2007
PREFERENTIAL EXPRESSION OF CHEMOKINE RECEPTOR CXCR4 BY HIGHLY MALIGNANT HUMAN GLIOMAS AND ITS ASSOCIATION WITH POOR PATIENT SURVIVAL
OBJECTIVECXCR4 is implicated in the growth, metastasis, and angiogenesis of malignant tumors. We investigated the potential role… 
2007
2007
A novel lipoxygenase inhibitor Nordy attenuates malignant human glioma cell responses to chemotactic and growth stimulating factors
Nordy is a chiral compound synthesized based on the structure of a natural lipoxygenase (LO) inhibitor nordihydroguaiaretic acid… 
2006
2006
Increased angiogenic capabilities of endothelial cells from microvessels of malignant human gliomas.
2006
2006
Nordy, a synthetic lipoxygenase inhibitor, inhibits the expression of formylpeptide receptor and induces differentiation of malignant glioma cells.
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