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nicotinylalanine

 
National Institutes of Health

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Review
2015
Review
2015
Multiple sclerosis is an inflammatory disease of the central nervous system, in which axonal transection takes place in parallel… Expand
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1999
1999
Endogenous excitotoxins have been implicated in degeneration of nigral dopaminergic neurons in Parkinson's disease. It may be… Expand
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Highly Cited
1998
Highly Cited
1998
Nicotinylalanine, an inhibitor of kynurenine metabolism, has been shown to elevate brain levels of endogenous kynurenic acid, an… Expand
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Highly Cited
1997
Highly Cited
1997
Endogenous excitotoxins have been implicated in the degeneration of dopaminergic neurons in the substantia nigra compacta of… Expand
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Highly Cited
1994
Highly Cited
1994
Kynurenate is an endogenous antagonist of the ionotropic glutamate receptors. It is synthesized from kynurenine, a tryptophan… Expand
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Highly Cited
1992
Highly Cited
1992
Abstract: Kynurenic acid (KYNA) was quantified in the extracellular spaces of the rat hippocampus using microdialysis and HPLC… Expand
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Highly Cited
1992
Highly Cited
1992
1. Nicotinylalanine is an analogue of kynurenine which has been reported to inhibit the enzymes kynurenine hydroxylase and… Expand
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Highly Cited
1991
Highly Cited
1991
: Quinolinic acid, an endogenous excitotoxin, and kynurenic acid, an antagonist of excitatory amino acid receptors, are believed… Expand
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1963
1963
Considerable evidence has been obtained that 3-hydroxyanthranilic acid and quinolinic acid can be converted to niacin in the… Expand
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