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neuron differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuron. [GOC:mah]
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

generation of neurons

Narrower (2)

neuron developmentneuron fate commitment

Papers overview

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Highly Cited
2015
Highly Cited
2015
FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a disorder of brain development. Most cases lack a clear etiology or genetic basis, and the… Expand
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Highly Cited
2009
Highly Cited
2009
Carbon nanotubes promote neuron differentiation from human embryonic stem cells.
Human embryonic stem cells (hESCs) hold great promise for regenerative medicine and transplantation therapy due to their self… Expand
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Highly Cited
2005
Highly Cited
2005
A Developmental Switch in the Response of DRG Neurons to ETS Transcription Factor Signaling
Two ETS transcription factors of the Pea3 subfamily are induced in subpopulations of dorsal root ganglion (DRG) sensory and… Expand
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Highly Cited
2001
Highly Cited
2001
Coordinate Regulation of Motor Neuron Subtype Identity and Pan-Neuronal Properties by the bHLH Repressor Olig2
Within the developing vertebrate nervous system, the mechanisms that coordinate neuronal subtype identity with generic features… Expand
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Highly Cited
2000
Highly Cited
2000
Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b.
Motor neurons are a widely studied model of vertebrate neurogenesis. They can be subdivided in somatic, branchial and visceral… Expand
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Highly Cited
1996
Highly Cited
1996
Requirement for LIM Homeobox Gene Isl1 in Motor Neuron Generation Reveals a Motor Neuron– Dependent Step in Interneuron Differentiation
Motor neuron differentiation is accompanied by the expression of a LIM homeodomain transcription factor, Islet1 (ISL1). To assess… Expand
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Highly Cited
1995
Highly Cited
1995
Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis
The differentiation of floor plate cells and motor neurons can be induced by Sonic hedgehog (SHH), a secreted signaling protein… Expand
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Highly Cited
1994
Highly Cited
1994
Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation.
To assess the functions of the retinoblastoma protein (RB) during normal development, we have analyzed mouse embryos that lack a… Expand
Highly Cited
1993
Highly Cited
1993
Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate
The identity of cell types generated along the dorsoventral axis of the neural tube depends on inductive signals that derive from… Expand
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Highly Cited
1992
Highly Cited
1992
Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1.
Motor neurons in the embryonic chick spinal cord express a homeobox gene, Islet-1, soon after their final mitotic division and… Expand
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