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Calcium fluxes have been implicated in the specification of the vertebrate embryonic nervous system for some time, but how these… Expand A forward genetic screen in the ascidian Ciona intestinalis identified a mutant line (frimousse) with a profound disruption in… Expand During early embryogenesis, Sox2 expression distinguishes the neural plate from other embryonic domains, suggesting that the… Expand Somatic development initiates from the epiblast in post-implantation mammalian embryos. Recent establishment of epiblast stem… Expand Cumulative evidence now indicates pivotal roles for the group B1 Sox genes, Sox1, Sox2 and Sox3 in the genesis and development of… Expand Introduction: Previous studies have shown that morphine administration could inhibit neural tube development in rat embryos and… Expand The expression of the transcription factor gene Sox2 precisely marks the neural plate in various vertebrate species. We… Expand The neural crest is a population of cells that originates at the interface between the neural plate and non-neural ectoderm. Here… Expand