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nerve growth factor processing

Known as: NGF processing, beta-nerve growth factor processing 
The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor. [GOC:mah, PMID:8615794]

Topic mentions per year

Topic mentions per year

1988-2012
01219882012

Papers overview

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Review
2012
Review
2012
Nerve Growth Factor and Alzheimer's Disease: New Facts for an Old Hypothesis
Understanding sporadic Alzheimer's disease (AD) onset and progression requires an explanation of what triggers the common core of… (More)
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2009
2009
Cell death and learning impairment in mice caused by in vitro modified pro-NGF can be related to its increased oxidative modifications in Alzheimer disease.
Pro-nerve growth factor (pro-NGF) is expressed at increased levels in Alzheimer's disease (AD)-affected brains and is able to… (More)
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Review
2005
Review
2005
'Mature' nerve growth factor is a minor species in most peripheral tissues.
The classic neurotrophin hypothesis is based on the idea that innervating neurons derive 'mature' neurotrophin provided by the… (More)
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Review
2001
Review
2001
Early days of the nerve growth factor proteins.
Adult male mouse submaxillary glands served as the preferred starting material for the isolation of the nerve growth factor (NGF… (More)
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Review
1991
Review
1991
Structure and biosynthesis of nerve growth factor.
Most of our knowledge about NGF comes from extensive study of the mouse submaxillary gland protein. NGF from this source is… (More)
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1988
1988
Processing and secretion of nerve growth factor: expression in mammalian cells with a vaccinia virus vector.
To study posttranslational mechanisms for the control of nerve growth factor (NGF), we used a recombinant vaccinia virus vector… (More)
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1988
1988
Use of vaccinia virus vectors to study protein processing in human disease. Normal nerve growth factor processing and secretion in cultured fibroblasts from patients with familial dysautonomia.
Familial dysautonomia is a hereditary disorder that affects autonomic and sensory neurons. Nerve growth factor (NGF) is required… (More)
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