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nephrotoxicity

 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
A Systematic Review of Strategies to Prevent Cisplatin-Induced Nephrotoxicity.
INTRODUCTION Cisplatin, a platinum-based antineoplastic agent, is the cornerstone for the treatment of many malignancies… Expand
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2017
2017
Protective effects of dioscin against doxorubicin-induced nephrotoxicity via adjusting FXR-mediated oxidative stress and inflammation.
Dioscin shows active effects against renal ischemia/reperfusion injury and lipopolysaccharide-induced inflammatory kidney injury… Expand
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2017
2017
Protective effect of Nigella sativa oil on cisplatin induced nephrotoxicity and oxidative damage in rat kidney.
BACKGROUND Nephrotoxicity is a severe complication in patients undergoing cisplatin (CP) chemotherapy. Previous studies in our… Expand
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2017
2017
3D Proximal Tubule Tissues Recapitulate Key Aspects of Renal Physiology to Enable Nephrotoxicity Testing
Due to its exposure to high concentrations of xenobiotics, the kidney proximal tubule is a primary site of nephrotoxicity and… Expand
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Highly Cited
2016
Highly Cited
2016
Ameliorative effect of berberine against gentamicin-induced nephrotoxicity in rats via attenuation of oxidative stress, inflammation, apoptosis and mitochondrial dysfunction
Abstract Background: Gentamicin (GM) is the commonly used antibiotics against Gram-negative infection, but the nephrotoxic… Expand
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Highly Cited
2016
Highly Cited
2016
A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro.
Nephrotoxicity due to drugs and environmental chemicals accounts for significant patient mortality and morbidity, but there is no… Expand
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Review
2015
Review
2015
DNA damage response in cisplatin-induced nephrotoxicity
Cisplatin and its derivatives are widely used chemotherapeutic drugs for cancer treatment. However, they have debilitating side… Expand
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Highly Cited
2014
Highly Cited
2014
Early prediction of polymyxin-induced nephrotoxicity with next-generation urinary kidney injury biomarkers.
Despite six decades of clinical experience with the polymyxin class of antibiotics, their dose-limiting nephrotoxicity remains… Expand
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Review
2013
Review
2013
Renoprotective effect of the antioxidant curcumin: Recent findings☆
For years, there have been studies based on the use of natural compounds plant-derived as potential therapeutic agents for… Expand
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Highly Cited
2002
Highly Cited
2002
Clinical and economic outcomes of conventional amphotericin B-associated nephrotoxicity.
A retrospective 9-year cohort study was conducted to identify the hospitalization costs, length of hospital stay, and mortality… Expand
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