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nepafenac

Known as: Nepafenacum, nepafenac [Chemical/Ingredient], Nepafenaco 
A topical nonsteroidal anti-inflammatory drug that is used in eye drops for the treatment of eye pain and swelling.
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

Anti-Inflammatory Agents, Non-SteroidalBenzeneacetamidesPhenylacetates

Narrower (1)

Nevanac
Nonsteroidal Anti-inflammatory Compounds [Chemical/Ingredient]nepafenac 1 MG/ML Ophthalmic Suspension [Nevanac]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Topical nepafenac for prevention of post-cataract surgery macular edema in diabetic patients: patient selection and perspectives
Since its first description, the prevention of pseudophakic cystoid macular edema (PCME) continues to pose challenges for… 
Review
2014
Review
2014
Efficacy and safety of pain relief medications after photorefractive keratectomy: review of prospective randomized trials.
Highly Cited
2009
Highly Cited
2009
Inhibition of surgically induced miosis and prevention of postoperative macular edema with nepafenac
Objective: To evaluate the effectiveness of prophylactic administration of nepafenac 0.1% in maintaining mydriasis and in… 
2009
2009
VITREOUS NONSTEROIDAL ANTIINFLAMMATORY DRUG CONCENTRATIONS AND PROSTAGLANDIN E2 LEVELS IN VITRECTOMY PATIENTS TREATED WITH KETOROLAC 0.4%, BROMFENAC 0.09%, AND NEPAFENAC 0.1%
Purpose: To assess vitreous concentrations of nonsteroidal antiinflammatory drugs (NSAIDs) and prostaglandin E2 in patients… 
Highly Cited
2008
Highly Cited
2008
Topical ophthalmic NSAIDs: a discussion with focus on nepafenac ophthalmic suspension
The removal of diclofenac sodium ophthalmic solution as a viable pharmaceutical entity in September 1999 from the US market… 
2007
2007
Analgesic and anti-inflammatory effectiveness of nepafenac 0.1% for cataract surgery
Background: To compare nepafenac 0.1% with placebo and ketorolac 0.5% for prevention and treatment of ocular pain and… 
Review
2007
Review
2007
Case of Corneal Melting Associated With the Use of Topical Nepafenac
Purpose: To report a case of corneal melting associated with the use of the topical nonsteroidal anti-inflammatory agent… 
Highly Cited
2003
Highly Cited
2003
Inflammation-Mediated Retinal Edema in the Rabbit Is Inhibited by Topical Nepafenac
The purpose of this study was to evaluate the ability of the nonsteroidal anti-inflammatory drug nepafenac to prevent development… 
Review
2003
Review
2003
Pharmacokinetics of topical ocular drug delivery: potential uses for the treatment of diseases of the posterior segment and beyond.
In developing a drug delivery strategy, issues of absorption, distribution, metabolism, and elimination must be considered. The… 
Highly Cited
2000
Highly Cited
2000
Nepafenac, a Unique Nonsteroidal Prodrug with Potential Utility in the Treatment of Trauma-Induced Ocular Inflammation: II. In Vitro Bioactivation and Permeation of External Ocular Barriers
Nepafenac, the amide analog of the NSAID amfenac, was examined in vitro for its bioactivation by ocular tissue components and its… 
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