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neoantigens

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Neoantigens in Hematologic Malignancies
T cell cancer neoantigens are created from peptides derived from cancer-specific aberrant proteins, such as mutated and fusion… 
2020
2020
Fusing Antigens and Adjuvants into Traceless Nanogels
Antigens and adjuvants were fused into “traceless” nanogels in order to produce an enhanced personalized cancer vaccine. 
Highly Cited
2019
Highly Cited
2019
Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade
Neoantigens (nAgs) are promising tumor antigens for cancer vaccination with the potential of inducing robust and selective T cell… 
2019
2019
Oncolytic adenovirus drives specific immune response generated by a poly-epitope pDNA vaccine encoding melanoma neoantigens into the tumor site
BackgroundDNA vaccines against cancer held great promises due to the generation of a specific and long-lasting immune response… 
2018
2018
Neoantigens in Ovarian Cancer: Embarrassment of Riches or Needles in a Haystack?
Comprehensive genomic and transcriptomic analysis demonstrate that tumor-infiltrating T lymphocytes that react to mutated… 
Highly Cited
2016
Highly Cited
2016
Low T-cell Receptor Diversity, High Somatic Mutation Burden, and High Neoantigen Load as Predictors of Clinical Outcome in Muscle-invasive Bladder Cancer.
Highly Cited
2000
Highly Cited
2000
Efficient priming of protein antigen-specific human CD4(+) T cells by monocyte-derived dendritic cells.
Dendritic cells (DCs) have the unique ability to initiate an immune response in vivo by capturing antigens (Ags) in peripheral… 
Highly Cited
1999
Highly Cited
1999
Inducing autoimmune disease to treat cancer.
For many years, visions for development of successful immunotherapy of cancer revolved around the induction of immune responses… 
Review
1993
Review
1993
Acetaldehyde/protein interactions: are they involved in the pathogenesis of alcoholic liver disease?
Alcohol abuse is a major cause of liver disease. While ethanol itself has been shown to be hepatotoxic, its primary metabolite… 
Highly Cited
1974
Highly Cited
1974
Neoantigens on spontaneous and carcinogen‐induced rat tumours defined by in vitro lymphocytotoxicity assays
Lymph‐node cells from rats bearing tumours apparently lacking in tumour rejection antigens were cytotoxic in vitro for cultured… 
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