FAQ

negative regulation of proline biosynthetic process

Known as: downregulation of proline biosynthesis, downregulation of proline synthesis, downregulation of proline biosynthetic process 
Any process that stops, prevents or reduces the frequency, rate or extent of proline biosynthetic process. [GOC:TermGenie, PMID:23415322]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1963-2017
05101519632017

Related topics

Related topics

2 relations

Broader (1)

biological control
proline biosynthetic process

Related mentions per year

Related mentions per year

1953-2018
1960198020002020
negative regulation of proline biosynthetic process
biological control
proline biosynthetic process

Papers overview

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2012
2012
Role of PPE18 Protein in Intracellular Survival and Pathogenicity of Mycobacterium tuberculosis in Mice
BACKGROUND Ever since its discovery the mycobacterial proline-proline-glutamic acid (PPE) family of proteins has generated a huge… (More)
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2011
2011
Steady-state kinetic mechanism of the proline:ubiquinone oxidoreductase activity of proline utilization A (PutA) from Escherichia coli.
The multifunctional proline utilization A (PutA) flavoenzyme from Escherichia coli performs the oxidation of proline to glutamate… (More)
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2009
2009
Erratum to: Characterization of two proline dipeptidases (prolidases) from the hyperthermophilic archaeon Pyrococcus horikoshii
Prolidases hydrolyze the unique bond between X-Pro dipeptides and can also cleave the P–F and P–O bonds found in organophosphorus… (More)
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2008
2008
Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers
Proline oxidase (POX), a flavoenzyme localized at the inner mitochondrial membrane, catalyzes the first step of proline… (More)
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2006
2006
Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis
Proline oxidase (POX), a mitochondrial inner-membrane protein, catalyzes the rate-limiting oxidation of proline to pyrroline- 5… (More)
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2005
2005
Characterization of a bifunctional PutA homologue from Bradyrhizobium japonicum and identification of an active site residue that modulates proline reduction of the flavin adenine dinucleotide…
PutA is a bifunctional flavoenzyme in bacteria that catalyzes the four-electron oxidation of proline to glutamate. In certain… (More)
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2003
2003
L-proline accumulation and freeze tolerance of Saccharomyces cerevisiae are caused by a mutation in the PRO1 gene encoding gamma-glutamyl kinase.
We previously isolated a mutant which showed a high tolerance to freezing that correlated with higher levels of intracellular L… (More)
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Highly Cited
2001
Highly Cited
2001
Structural organization and regulation of the small proline-rich family of cornified envelope precursors suggest a role in adaptive barrier function.
The protective barrier provided by stratified squamous epithelia relies on the cornified cell envelope (CE), a structure… (More)
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1992
1992
Oxidation of L-thiazolidine-4-carboxylate by L-proline dehydrogenase in Escherichia coli.
L-Thiazolidine-4-carboxylate (T4C, gamma-thioproline) is a toxic analogue of L-proline. T4C can be oxidized by Escherichia coli… (More)
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1986
1986
Structures of two HaeIII-type genes in the human salivary proline-rich protein multigene family.
Two members of the human salivary proline-rich protein (PRP) multigene family have been isolated and completely sequenced. These… (More)
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