negative T cell selection

Known as: negative T lymphocyte selection, negative T-cell selection, negative T-lymphocyte selection 
The process of elimination of immature T cells which react strongly with self-antigens. [ISBN:0781735149, PMID:12414722]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2011
01219972011

Papers overview

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Review
2011
Review
2011
Apoptosis is a natural process where cells that are no longer required can be eliminated in a highly regulated, controlled manner… (More)
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2009
2009
Protein tyrosine phosphatase, non-receptor type 22 (PTPN22) inhibits T-cell activation and interleukin-2 (IL-2) production. The… (More)
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2007
2007
Thymomas are thymic epithelial neoplasms, associated with a variety of autoimmune disorders (especially myasthenia gravis), that… (More)
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2001
2001
We assessed the safety and efficacy of autologous stem cell transplantation (ASCT) using T cell depleted grafts in the treatment… (More)
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2000
2000
Engraftment of allogeneic bone marrow (BM) has been shown to induce tolerance to organs genotypically matched with the BM donor… (More)
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2000
2000
The diversity of the T cell receptor (TCR) repertoire is limited, because of the processes of positive and negative T cell… (More)
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1998
1998
Thymocytes form unique multicellular complexes with epithelial cells (thymic nurse cells, TNC) and rosettes (ROS) with… (More)
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1997
1997
Little is known about the molecular mechanisms and transcriptional regulation that govern T cell selection processes and the… (More)
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