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mycolactone B

National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Macrolides

Papers overview

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2017
2017
ONIOM Method Characterization of Hydrogen Bonding Sites of Mycolactone A/B, a Buruli Ulcer Toxin
Mycolactone molecules are responsible of Buruli ulcer disease. In this work, we are interested in the geometric, energetic and… 
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2017
2017
Modular total syntheses of mycolactone A/B and its [2H]-isotopologue.
A modular total synthesis of mycolactone A/B, the exotoxin produced by Mycobacterium ulcerans, has been achieved through the… 
2016
2016
Mycolactone-mediated neurite degeneration and functional effects in cultured human and rat DRG neurons
Background Mycolactone is a polyketide toxin secreted by the mycobacterium Mycobacterium ulcerans, responsible for the extensive… 
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2014
2014
Accelerated Detection of Mycolactone Production and Response to Antibiotic Treatment in a Mouse Model of Mycobacterium ulcerans Disease
Diagnosis of the neglected tropical disease, Buruli ulcer, can be made by acid-fast smear microscopy, specimen culture on… 
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2012
2012
Photochemistry of mycolactone A/B, the causative toxin of Buruli ulcer.
Photochemistry of mycolactone A/B and related unsaturated fatty acid esters is reported. On exposure to visible light… 
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Highly Cited
2011
Highly Cited
2011
Chemistry of mycolactones, the causative toxins of Buruli ulcer
  • Y. Kishi
  • Proceedings of the National Academy of Sciences
  • 2011
  • Corpus ID: 26617036
Buruli ulcer is a severe and devastating skin disease caused by Mycobacterium ulcerans infection, yet it is one of the most… 
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2010
2010
Detection of Mycolactone A/B in Mycobacterium ulcerans–Infected Human Tissue
Background Mycobacterium ulcerans disease (Buruli ulcer) is a neglected tropical disease common amongst children in rural West… 
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2010
2010
A Mycobacterium ulcerans toxin, mycolactone, induces apoptosis in primary human keratinocytes and in HaCaT cells.
The pathogenicity of Mycobacterium ulcerans (Buruli ulcer) depends on cytotoxic effect of its exotoxin mycolactone. Since… 
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Highly Cited
2005
Highly Cited
2005
A Newly Discovered Mycobacterial Pathogen Isolated from Laboratory Colonies of Xenopus Species with Lethal Infections Produces a Novel Form of Mycolactone, the Mycobacterium ulcerans Macrolide Toxin
ABSTRACT Mycobacterium ulcerans, the causative agent of Buruli ulcer, produces a macrolide toxin, mycolactone A/B, which is… 
Highly Cited
2003
Highly Cited
2003
Uptake and cellular actions of mycolactone, a virulence determinant for Mycobacterium ulcerans.
Mycolactone is a macrolide secreted by Mycobacterium ulcerans. Experimental evidence suggests that mycolactone plays a prominent… 
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