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mycograb

 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Invasive candidiasis (IC) represents the leading fungal infection of humans causing life-threatening disease in immunosuppressed… Expand
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2012
2012
Mycograb C28Y is a recombinant human antibody fragment thought to target HSP-90 and potentiate amphotericin B (AMB). Absence of… Expand
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2011
2011
Systemic candidiasis causes significant mortality in patients despite amphotericin B (AMB) therapy. Mycograb C28Y variant, a… Expand
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2008
2008
Efungumab (Mycograb®) is a human recombinant antibody against fungal Hsp90 that, in combination with lipid-associated… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Mycograb (NeuTec Pharma) is a human recombinant monoclonal antibody against heat shock protein 90 that, in laboratory… Expand
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2005
2005
This article reported the identification of heat shock protein 90 (hsp90) homologues by immunoblot in Cryptococcus neoformans… Expand
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2005
2005
Systemic infection by Candida species in the United States still tags with it a significant 35-40% mortality rate and data does… Expand
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Review
2004
Review
2004
Historically, the therapy of serious fungal infection has been dominated by monotherapy with the polyene antibiotic amphotericin… Expand
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Highly Cited
2003
Highly Cited
2003
Mycograb (NeuTec Pharma plc) is a human genetically recombinant antibody against fungal heat shock protein 90 (HSP90). Antibody… Expand
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Review
2003
Review
2003
Advances in antibody engineering have solved many of the problems inherent in traditional sources of antibodies, and about a… Expand
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