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mycograb

 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Invasive candidiasis (IC) represents the leading fungal infection of humans causing life-threatening disease in immunosuppressed… Expand
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2012
2012
ABSTRACT Mycograb C28Y is a recombinant human antibody fragment thought to target HSP-90 and potentiate amphotericin B (AMB… Expand
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2011
2011
ABSTRACT Systemic candidiasis causes significant mortality in patients despite amphotericin B (AMB) therapy. Mycograb C28Y… Expand
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2008
2008
Efungumab (Mycograb®) is a human recombinant antibody against fungal Hsp90 that, in combination with lipid-associated… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Mycograb (NeuTec Pharma) is a human recombinant monoclonal antibody against heat shock protein 90 that, in laboratory… Expand
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Highly Cited
2005
Highly Cited
2005
This article reported the identification of heat shock protein 90 (hsp90) homologues by immunoblot in Cryptococcus neoformans… Expand
2005
2005
Systemic infection by Candida species in the United States still tags with it a significant 35-40% mortality rate and data does… Expand
Review
2004
Review
2004
Historically, the therapy of serious fungal infection has been dominated by monotherapy with the polyene antibiotic amphotericin… Expand
Highly Cited
2003
Highly Cited
2003
ABSTRACT Mycograb (NeuTec Pharma plc) is a human genetically recombinant antibody against fungal heat shock protein 90 (HSP90… Expand
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Review
2003
Review
2003
Advances in antibody engineering have solved many of the problems inherent in traditional sources of antibodies, and about a… Expand