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motuporin

Known as: nodularin V, nodularin-V 
National Institutes of Health

Related topics

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1 relation

Broader (1)

Cyclic Peptides

Papers overview

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Highly Cited
2008
Highly Cited
2008
Co-occurrence of beta-N-methylamino-L-alanine, a neurotoxic amino acid with other cyanobacterial toxins in British waterbodies, 1990-2004.
The neurotoxic amino acid, beta-N-methylamino-L-alanine, was found to be present in all of 12 analysed samples of cyanobacterial… 
2007
2007
A serendipitous discovery of isomotuporin-containing sponge populations of Theonella swinhoei.
An in-depth LCMS examination of 14 different collections of Indo-Pacific Theonella swinhoei sponges resulted in the discovery of… 
Highly Cited
2006
Highly Cited
2006
Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins.
2005
2005
Heterogeneity of nodularin bioaccumulation in northern Baltic Sea flounders in 2002.
2002
2002
Enantioselective synthesis of the protein phosphatase inhibitor (-)-motuporin.
  • T. Hu, J. Panek
  • Journal of the American Chemical Society
  • 2002
  • Corpus ID: 19719863
A highly convergent asymmetric synthesis of the protein phosphatase inhibitor motuporin 1a is described. Synthesis and coupling… 
1999
1999
Total Synthesis of Motuporin and 5-[L-Ala]-Motuporin.
Total synthesis of the cyclic peptide hepatotoxin motuporin is described, including an efficient synthesis of the constituent… 
Highly Cited
1997
Highly Cited
1997
A Molecular Basis for Different Interactions of Marine Toxins with Protein Phosphatase-1
The hepatotoxic cyclic heptapeptide microcystins and cyclic pentapeptide nodularins are powerful liver tumor promoters and potent… 
Highly Cited
1996
Highly Cited
1996
Molecular mechanisms underlying he interaction of motuporin and microcystins with type-1 and type-2A protein phosphatases.
Heptapeptide microcystin and pentapeptide motuporin (nodularin-V) are equipotent inhibitors of type-1 and type-2A protein… 
Highly Cited
1995
Highly Cited
1995
Comparison of the solution structures of microcystin-LR and motuporin
A comparison of the structures of two cyanobacterial toxins yields insights into how they may inhibit protein phosphatase-1 and… 
Highly Cited
1993
Highly Cited
1993
Identification and characterization of hydrophobic microcystins in Canadian freshwater cyanobacteria.
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