motuporin

The neurotoxic amino acid, beta-N-methylamino-L-alanine, was found to be present in all of 12 analysed samples of cyanobacterial… Expand

An in-depth LCMS examination of 14 different collections of Indo-Pacific Theonella swinhoei sponges resulted in the discovery of… Expand

The microcystins and nodularins are tumour promoting hepatotoxins that are responsible for global adverse human health effects… Expand

The cyanobacterial hepatotoxin nodularin is abundantly produced by the cyanobacterium Nodularia spumigena in the Baltic Sea… Expand

A highly convergent asymmetric synthesis of the protein phosphatase inhibitor motuporin 1a is described. Synthesis and coupling… Expand

Total synthesis of the cyclic peptide hepatotoxin motuporin is described, including an efficient synthesis of the constituent… Expand

The hepatotoxic cyclic heptapeptide microcystins and cyclic pentapeptide nodularins are powerful liver tumor promoters and potent… Expand

Heptapeptide microcystin and pentapeptide motuporin (nodularin-V) are equipotent inhibitors of type-1 and type-2A protein… Expand

A comparison of the structures of two cyanobacterial toxins yields insights into how they may inhibit protein phosphatase-1 and… Expand

Hepatotoxic microcystins produced by cyanobacteria in freshwater lakes represent a significant health hazard to humans and… Expand