morphogenesis of a polarized epithelium

Known as: epithelial polarization 
The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization
Arthrogryposis, renal dysfunction and cholestasis syndrome (ARC) is a multisystem disorder associated with abnormalities in… (More)
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Highly Cited
2009
Highly Cited
2009
Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization
Dishevelled (Dsh) is a cytoplasmic multidomain protein that is required for all known branches of the Wnt signalling pathway. The… (More)
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Highly Cited
2007
Highly Cited
2007
Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization
The molecular mechanisms of how primordial adherens junctions (AJs) evolve into spatially separated belt-like AJs and tight… (More)
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Highly Cited
2007
Highly Cited
2007
Liver progenitor cells develop cholangiocyte-type epithelial polarity in three-dimensional culture.
Cholangiocytes are cellular components of the bile duct system of the liver, which originate from hepatoblasts during embryonic… (More)
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Highly Cited
2005
Highly Cited
2005
Actin at cell-cell junctions is composed of two dynamic and functional populations.
The ability of epithelial cells to polarize requires cell-cell adhesion mediated by cadherin receptors. During cell-cell contact… (More)
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Highly Cited
2005
Highly Cited
2005
Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells
Epithelial polarization involves the segregation of apical and basolateral membrane domains, which are stabilized and maintained… (More)
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Highly Cited
2003
Highly Cited
2003
The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells.
In Drosophila, the Crumbs-Stardust-Discs-lost complex is required during the establishment of polarized epithelia. Embryos that… (More)
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Highly Cited
2002
Highly Cited
2002
Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-beta1 and Ha-Ras: steps towards invasiveness.
In hepatocarcinogenesis, it is an open question whether transforming growth factor (TGF)-beta1 provides a tumor-suppressive or a… (More)
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Highly Cited
2002
Highly Cited
2002
A role for dystroglycan in epithelial polarization: loss of function in breast tumor cells.
Receptors mediating cell-basement membrane interactions are potent regulators of epithelial architecture and function, and… (More)
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Highly Cited
2001
Highly Cited
2001
Na,K-ATPase beta-subunit is required for epithelial polarization, suppression of invasion, and cell motility.
The cell adhesion molecule E-cadherin has been implicated in maintaining the polarized phenotype of epithelial cells and… (More)
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