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ABSTRACT In order to determine the pharmacokinetic disposition of chloroquine (CQ) and its active metabolite, desethylchloroquine… Expand SummaryTwenty-one healthy Nigerian volunteers distributed into four groups participated in a study to determine the significance… Expand A method for simultaneous analysis of chloroquine, proguanil and their metabolites from a whole blood sample (80 microL) dried on… Expand INTRODUCTION
Over 2 million children globally are HIV positive. More than 90% are infected in utero from their mothers. Current… Expand Our objective was to develop a bioassay method based on the isotopic microtest of Desjardins and to validate it by comparing the… Expand Chloroquine, monodesethylchloroquine, diazepam, and nordiazepam levels are simultaneously determined in whole blood or plasma by… Expand Eight healthy volunteers who had not taken chloroquine 2 to 12 months previously participated in a single dose study designed to… Expand A controlled study was carried out in ten healthy, male volunteers (randomly distributed into control and test groups of five… Expand Using thin-layer and gas chromatography and mass spectrometry, chloroquine and its major metabolite (monodesethylchloroquine… Expand