mobilferrin
National Institutes of Health
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There are two pathways for inorganic iron uptake in the intestine, the ferric pathway, mediated by the key protein mobilferrin…
Inorganic iron can be transported into cells in the absence of transferrin. Ferric iron enters cells utilizing an integrin…
The absorption of metal ions in the mammalian single-stomached gut is fortunately highly selective, and both luminal and tissue…
Dietary inorganic iron is mostly ferric iron. This is solubilized at the acid pH level of the stomach where it chelates mucins…
Heme iron is absorbed from meat more efficiently than dietary inorganic iron and in a different manner. Thus, iron deficiency is…
Iron transport in reticulocytes is known to occur via the well‐described transferrin‐receptor–endosome pathway. An alternative…
Iron is bound to transferrin in the plasma. A specific receptor on the cell surface binds transferrin and internalizes…
Recent studies reported that iron salts were absorbed in the duodenum utilizing a pathway involving membrane-associated integrin…
A mechanism for the absorption of inorganic iron in the small intestine is described in which integrins appear to play an…